AI481877 Antibody (G-4): sc-515516

AI481877 Antibody (G-4) is a mouse monoclonal IgM kappa antibody that detects the AI481877 protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AI481877 (G-4) antibody is available as the non-conjugated form. AI481877 monoclonal antibody (G-4) targets a protein located on chromosome 9, which plays a crucial role in various genetic functions, including gender determination and vascular integrity regulation. Specifically, the distal portion of 9p is associated with sex reversal phenomena, where deletions can lead to the development of a female phenotype in individuals with a male X,Y genotype. Additionally, chromosome 9 harbors genes linked to hereditary hemorrhagic telangiectasia, such as the Endoglin protein (ENG), which is vital for maintaining vascular stability. The presence of AI481877 protein in this genomic context underscores its potential involvement in critical biological processes and disease mechanisms, making anti-AI481877 antibody (G-4) an essential tool for researchers studying these pathways in mouse models.

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AI481877 Antibody (G-4) References:

1. DNA sequence and analysis of human chromosome 9.  |  Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
2. BCR-ABL activates STAT3 via JAK and MEK pathways in human cells.  |  Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
3. BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.  |  Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
4. Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia.  |  Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
5. Phenotypic and cytogenetic spectrum of 9p trisomy.  |  Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
6. Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia.  |  Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
7. Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease).  |  Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
8. A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect.  |  Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
9. Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia.  |  Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-AI481877 Antibody (G-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-AI481877 Antibody (G-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

AI481877 Antibody (G-4) Specifications

Alternate Product Name: AI481877

Product Clone Name: G-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 1064-1090

Epitope Target: AI481877

Epitope Species: mouse

Product Reactivity/Detection: AI481877

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for AI481877 Antibody (G-4): P: Blocking Peptide