AGP-1 Antibody (29A1): sc-69753
- AGP-1 Antibody (29A1) is a mouse monoclonal IgG1 AGP-1 antibody, cited in 1 publications, provided at 100 µl
- raised against purified AGP 1 of human origin
- recommended for detection of AGP-1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for AGP-1 Antibody (29A1). This work is in progress.
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AGP-1 Antibody (29A1) is a mouse monoclonal IgG1 antibody that detects AGP-1 protein of human origin by western blotting (WB) and immunoprecipitation (IP). AGP-1 (29A1) antibody is available as the non-conjugated form. AGP-1, also known as α1-acid glycoprotein, is a crucial acute phase plasma protein synthesized in the liver, playing a significant role in the body′s response to inflammation and infection. AGP-1 is involved in regulating the interaction between blood cells and endothelial cells, which is vital for maintaining vascular integrity and facilitating the movement of immune cells to sites of injury or infection. AGP-1 expression is notably induced by acute-phase stimulatory agents, such as bacterial lipopolysaccharides, and plasma levels typically range from 0.5 to 1.4 mg/ml, increasing significantly during acute inflammatory responses. This elevation makes AGP-1 a valuable biomarker for diagnosing inflammatory conditions. Additionally, AGP-1 and AGP-2 possess multiple potential N-glycosylation sites, which are important for stability and function. Abnormal expression of AGP-1 has been linked to various immunogenetic diseases, including sarcoidosis, while mutations in AGP-2 are associated with different types of carcinomas, highlighting the clinical relevance in disease pathology.
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AGP-1 Antibody (29A1) References:
- Seroprevalence of hepatitis C virus infection and its association with natural infection of hepatitis B virus among preschool children in Taiwan. | Lin, DB., et al. 2003. Eur J Epidemiol. 18: 245-9. PMID: 12800949
- Structure and expression of mouse alpha 1-acid glycoprotein gene-3 (AGP-3). | Chang, CJ., et al. 1992. DNA Cell Biol. 11: 315-20. PMID: 1605854
- Identification of the bovine alpha1-acid glycoprotein in colostrum and milk. | Ceciliani, F., et al. 2005. Vet Res. 36: 735-46. PMID: 16120249
- Study of the pH-dependent conformational changes in alpha1-acid glycoprotein using FRET. | Mikhailov, AS. 2005. Ann N Y Acad Sci. 1048: 453-6. PMID: 16154976
- Selective binding of coumarin enantiomers to human alpha1-acid glycoprotein genetic variants. | Hazai, E., et al. 2006. Bioorg Med Chem. 14: 1959-65. PMID: 16290938
- Differential expression of the mouse alpha 1-acid glycoprotein genes (AGP-1 and AGP-2) during inflammation and aging. | Carter, KC., et al. 1991. Biochim Biophys Acta. 1089: 197-205. PMID: 2054382
- Molecular cloning of cDNAs corresponding to two genes of alpha 1-acid glycoprotein and characterization of two alleles of AGP-1 in the mouse. | Lee, SC., et al. 1989. DNA. 8: 245-51. PMID: 2475311
- Orosomucoid (ORM) typing by print lectinofixation: a new technique for isoelectric focusing. Two common alleles in Japan. | Umetsu, K., et al. 1985. Hum Genet. 71: 223-4. PMID: 4065894
- Synergistic interaction between ORM1 and C3 types in disease associations. | Fan, C., et al. 1995. Exp Clin Immunogenet. 12: 92-5. PMID: 7576721
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AGP-1 Antibody (29A1) | sc-69753 | 100 µl | $322.00 |