AFP/Alpha fetoprotein Antibody (F-8): sc-166325

AFP Antibody (F-8) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect alpha-fetoprotein (AFP), a crucial plasma protein primarily expressed in the fetal liver during development. AFP plays a significant role in transporting essential molecules such as copper, nickel, and fatty acids, and can interact with serum albumin or estrogen under certain conditions. In normal adult tissues, AFP levels are minimal; however, elevated concentrations are strongly associated with hepatocellular carcinomas and serve as a reliable tumor marker for monitoring tumor growth and progression. Anti-AFP antibody (F-8) is raised against amino acids 171-310 of human AFP and exhibits broad species reactivity, including mouse, rat, and human AFP, making it versatile for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). By targeting a specific epitope on AFP, AFP (F-8) antibody ensures accurate detection and quantification, which is essential for both research and clinical diagnostics. Understanding AFP′s regulatory mechanisms, including its interactions with transcription factors like NF-1 and HNF-1, highlights the importance of precise detection tools like AFP (F-8) monoclonal antibody in advancing cancer research and improving patient outcomes. Whether used in laboratory settings or clinical environments, anti-AFP antibody (F-8) provides reliable performance for studying AFP′s function and its role as a biomarker in various diseases.

The preferred AFP/Alpha fetoprotein antibody is AFP/Alpha fetoprotein Antibody (C3): sc-8399.