ADRM1 Antibody (G-3): sc-374018
- ADRM1 Antibody (G-3) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-29 at the N-terminus of ADRM1 of human origin
- recommended for detection of ADRM1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ADRM1 Antibody (G-3) for WB and IHC(P) applications. These reagents are now offered in bundles with ADRM1 Antibody (G-3) (see ordering information below).
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ADRM1 Antibody (G-3) is a mouse monoclonal IgG2a antibody that detects ADRM1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ADRM1, also known as adhesion-regulating molecule 1, GP110, ARM-1, or Rpn13, is a 407 amino acid protein that plays a crucial role in cellular processes by facilitating protein recruitment and cell adhesion. ADRM1 is primarily located in both the nucleus and cytoplasm, which enables participation in diverse cellular functions, including UCH-L5 recruitment to the 26S proteasome, thereby enhancing proteasome activity. Furthermore, ADRM1 mediates lymphocyte adhesion to endothelial cells, suggesting involvement in lymphocyte homing, which is essential for immune response and tissue repair. Notably, interferon-gamma induces ADRM1 expression in certain cancer cell lines, and ADRM1 is upregulated in various metastatic cells, indicating potential role in carcinogenesis. Additionally, two ADRM1 isoforms arise from alternative splicing events, which may contribute to functional diversity in different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADRM1 Antibody (G-3) | sc-374018 | 200 µg/ml | $322.00 | |||
ADRM1 Antibody (G-3): m-IgG Fc BP-HRP Bundle | sc-537904 | 200 µg Ab; 10 µg BP | $361.00 | |||
ADRM1 Antibody (G-3): m-IgGκ BP-HRP Bundle | sc-535368 | 200 µg Ab; 40 µg BP | $361.00 | |||
ADRM1 Antibody (G-3): m-IgG2a BP-HRP Bundle | sc-548144 | 200 µg Ab; 10 µg BP | $361.00 | |||
ADRM1 (G-3) Neutralizing Peptide | sc-374018 P | 100 µg/0.5 ml | $69.00 |