ADM Antibody (HTA91a/G2): sc-53154

ADM Antibody (HTA91a/G2) is a mouse monoclonal IgM antibody that detects adrenomedullin (ADM) in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ADM is a crucial vasodilator produced by various contractile cells, playing a significant role in regulating fluid and electrolyte balance as well as maintaining cardiovascular health. ADM (HTA91a/G2) antibody targets a protein involved in blood pressure modulation, with ADM levels often elevated in hypertensive patients, indicating importance in cardiovascular pathophysiology. ADM is primarily located in the vascular endothelium and adrenal medulla, where secretion into the bloodstream allows systemic effects. This localization enables ADM to act quickly on target tissues, influencing renal function and promoting natriuresis, which is the excretion of sodium in urine. ADM′s ability to increase glomerular filtration rate while decreasing sodium reabsorption in the distal tubules underscores importance in fluid homeostasis and blood pressure regulation. Furthermore, ADM′s presence in the central nervous system allows modulation of appetite and energy balance, highlighting multifaceted roles in both cardiovascular and metabolic processes. With diverse functions and critical involvement in various physiological pathways, anti-ADM antibody (HTA91a/G2) serves as an essential tool for researchers studying cardiovascular health and related disorders.