ACTR10 Antibody (E-6): sc-515293
- ACTR10 Antibody (E-6) is a mouse monoclonal IgG1 κ ACTR10 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-18 at the N-terminus of ACTR10 of human origin
- ACTR10 Antibody (E-6) is recommended for detection of ACTR10 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ACTR10 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ACTR10 Antibody (E-6) for WB applications. These reagents are now offered in bundles with ACTR10 Antibody (E-6) (see ordering information below).
ACTR10 Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects ACTR10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACTR10 (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ACTR10 protein, also known as Actin-related protein 10, ARP11, or HARP11, consists of 417 amino acids and is primarily located in the cytoplasm and cytoskeleton, playing a crucial role in cellular structure and motility. ACTR10 is a member of the actin family, which is essential for various cellular processes, including maintaining cell shape, enabling cell movement, and facilitating intracellular transport. Proper functioning of ACTR10 is vital for normal cellular dynamics, and dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders. ACTR10 gene is situated on human chromosome 14, a region that harbors approximately 700 genes and is associated with significant genetic conditions, such as Alzheimer′s disease and α1-antitrypsin deficiency. Using anti-ACTR10 antibody (E-6) in research can provide valuable insights into the role of ACTR10 in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACTR10 Antibody (E-6) References:
- The DNA sequence and analysis of human chromosome 14. | Heilig, R., et al. 2003. Nature. 421: 601-7. PMID: 12508121
- Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. | Eckley, DM. and Schroer, TA. 2003. Mol Biol Cell. 14: 2645-54. PMID: 12857853
- A presenilin 1 R278I mutation presenting with language impairment. | Godbolt, AK., et al. 2004. Neurology. 63: 1702-4. PMID: 15534260
- Pathological and physiological functions of presenilins. | Vetrivel, KS., et al. 2006. Mol Neurodegener. 1: 4. PMID: 16930451
- Presenilin-1 mutation E318G and familial Alzheimer's disease in the Italian population. | Albani, D., et al. 2007. Neurobiol Aging. 28: 1682-8. PMID: 16952411
- A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation. | Martín-Subero, JI., et al. 2007. Leukemia. 21: 1532-44. PMID: 17495977
- The genetics of very early onset Alzheimer disease. | Filley, CM., et al. 2007. Cogn Behav Neurol. 20: 149-56. PMID: 17846513
- The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency. | Cruz, PE., et al. 2007. Pharmacogenomics. 8: 1191-8. PMID: 17924834
- Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management. | Stolk, J., et al. 2006. Int J Chron Obstruct Pulmon Dis. 1: 151-60. PMID: 18046892
- In vitro screen of prion disease susceptibility genes using the scrapie cell assay. | Brown, CA., et al. 2014. Hum Mol Genet. 23: 5102-8. PMID: 24833721
- Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons. | Drerup, CM., et al. 2017. Elife. 6: PMID: 28414272
- Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo. | Herbert, AL., et al. 2017. Proc Natl Acad Sci U S A. 114: E9153-E9162. PMID: 29073112
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACTR10 Antibody (E-6) | sc-515293 | 200 µg/ml | $322.00 | |||
ACTR10 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-528017 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACTR10 Antibody (E-6): m-IgG1 BP-HRP Bundle | sc-533390 | 200 µg Ab; 20 µg BP | $361.00 | |||
ACTR10 Antibody (E-6) AC | sc-515293 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ACTR10 Antibody (E-6) HRP | sc-515293 HRP | 200 µg/ml | $322.00 | |||
ACTR10 Antibody (E-6) FITC | sc-515293 FITC | 200 µg/ml | $336.00 | |||
ACTR10 Antibody (E-6) PE | sc-515293 PE | 200 µg/ml | $349.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 488 | sc-515293 AF488 | 200 µg/ml | $364.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 546 | sc-515293 AF546 | 200 µg/ml | $364.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 594 | sc-515293 AF594 | 200 µg/ml | $364.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 647 | sc-515293 AF647 | 200 µg/ml | $364.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 680 | sc-515293 AF680 | 200 µg/ml | $364.00 | |||
ACTR10 Antibody (E-6) Alexa Fluor® 790 | sc-515293 AF790 | 200 µg/ml | $364.00 | |||
ACTR10 (E-6) Neutralizing Peptide | sc-515293 P | 100 µg/0.5 ml | $69.00 |