

ACTR-IB Antibody (J07F) is a rat monoclonal IgG2a antibody that detects ACTR-IB in mouse samples through western blotting (WB) and immunoprecipitation (IP) applications. ACTR-IB, also known as ALK-4 or SKR2, is a member of the activin receptor family, which plays a crucial role in mediating cellular responses to transforming growth factor beta superfamily ligands. Anti-ACTR-IB antibody (J07F) targets a receptor primarily located on the cell membrane, where ACTR-IB forms a heteromeric complex with type II receptors, facilitating the activation of downstream signaling pathways that influence gene expression, cell differentiation, and morphogenesis. ACTR-IB is vital for various physiological processes, including embryonic development and tissue homeostasis, as ACTR-IB regulates the balance between cell proliferation and differentiation. Dysregulation of ACTR-IB has been implicated in several pathological conditions, including cancer and fibrotic diseases, making ACTR-IB an important target for therapeutic intervention. ACTR-IB monoclonal antibody (J07F) is an essential tool for researchers aiming to explore the intricate signaling mechanisms mediated by ACTR-IB and its role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACTR-IB Antibody (J07F) | sc-73678 | 100 µg/ml | $322.00 |