ACTL7B Antibody (K30): sc-100912
- ACTL7B Antibody (K30) is a mouse monoclonal IgG2a κ provided at 50 µg/0.5 ml
- raised against recombinant ACTL7B of human origin
- recommended for detection of ACTL7B of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ACTL7B Antibody (K30). This work is in progress.
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ACTL7B Antibody (K30) is a mouse monoclonal IgG2a light chain antibody that detects ACTL7B in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). ACTL7B, also known as actin-like 7B, plays a crucial role in various cellular processes, including spindle orientation, nuclear migration, and chromatin remodeling, which are essential for proper cell division and genomic stability. ACTL7B is primarily localized in the cytoplasm and is notably expressed in the testis and prostate, highlighting its potential significance in reproductive biology. With a length of 415 amino acids, ACTL7B is encoded by a gene located on chromosome 9, which is situated in a head-to-head orientation with the familial dysautonomia candidate region; however, ACTL7B is not implicated in the pathogenesis of this genetic disorder. ACTL7B exhibits high sequence similarity with ACTL7A, sharing 88% identity between human and mouse proteins, and contains key phosphorylation sites, including one for protein kinase C and another for cAMP/cGMP-dependent kinases, which are critical for regulating activity and interactions. Anti-ACTL7B antibody (K30) is an invaluable tool for researchers investigating the functional dynamics of this actin-related protein in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACTL7B Antibody (K30) | sc-100912 | 50 µg/0.5 ml | $322.00 |