ACSL5 Antibody (E-12): sc-398310
- ACSL5 Antibody (E-12) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 73-104 near the N-terminus of ACSL5 of human origin
- recommended for detection of short and long isoforms of ACSL5 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ACSL5 Antibody (E-12) for WB applications. These reagents are now offered in bundles with ACSL5 Antibody (E-12) (see ordering information below).
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ACSL5 Antibody (E-12) is a mouse monoclonal IgG1 antibody that detects ACSL5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACSL5, a member of the acyl-CoA synthetase family, plays a crucial role in lipid metabolism by catalyzing the conversion of long-chain fatty acids into acyl-CoA derivatives, which are essential for various metabolic pathways, including the synthesis of triacylglycerols and phospholipids. ACSL5 is predominantly localized in the mitochondrion, microsome, and peroxisome, highlighting its importance in cellular energy homeostasis and lipid biosynthesis. Notably, ACSL5 exhibits a preference for C16-C18 unsaturated fatty acids, making ACSL5 vital for the metabolism of these lipids in tissues such as the uterus and spleen, where ACSL5 is highly expressed. Furthermore, a decrease in ACSL5 expression has been linked to tumorigenesis, particularly in endometrioid adenocarcinomas and colorectal carcinomas, underscoring ACSL5′s potential as a biomarker for cancer progression and a target for therapeutic intervention. Anti-ACSL5 antibody (E-12) is an invaluable tool for researchers investigating lipid metabolism and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACSL5 Antibody (E-12) | sc-398310 | 200 µg/ml | $322.00 | |||
ACSL5 Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-540930 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACSL5 Antibody (E-12): m-IgG1 BP-HRP Bundle | sc-542471 | 200 µg Ab; 20 µg BP | $361.00 | |||
ACSL5 (E-12) Neutralizing Peptide | sc-398310 P | 100 µg/0.5 ml | $69.00 |