Acidic Cytokeratin Antibody (AE1): sc-58719
- Acidic Cytokeratin Antibody (AE1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against epidermal keratins of human origin
- recommended for detection of most acidic (type I) cytokeratins of mouse, rat, human, bovine and rabbit origin by WB, IP, IF and IHC(P)
- available conjugated to FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Acidic Cytokeratin Antibody (AE1) for WB and IHC(P) applications. These reagents are now offered in bundles with Acidic Cytokeratin Antibody (AE1) (see ordering information below).
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SEE ALSO...
Acidic Cytokeratin Antibody (AE1) is a mouse monoclonal IgG1 antibody that detects Acidic Cytokeratin in mouse, rat, human, bovine, and rabbit samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Acidic Cytokeratin antibody (AE1) targets a crucial subset of cytokeratins, which are integral to the structural framework of epithelial cells, comprising up to 85% of mature keratinocytes in the vertebrate epidermis. These proteins are essential for maintaining cellular integrity and facilitating tissue differentiation, making them significant markers in the study of various malignancies. The acidic cytokeratins, characterized by their low molecular weight and isoelectric point of less than 5.7, are particularly important in the context of epithelial tissue pathology, as they can indicate the differentiation status of tumors. Understanding the expression and regulation of these cytokeratins is vital for developing targeted therapies and diagnostic tools in oncology, as their presence or absence can provide insights into tumor behavior and patient prognosis.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acidic Cytokeratin Antibody (AE1) | sc-58719 | 200 µg/ml | $316.00 | |||
Acidic Cytokeratin Antibody (AE1): m-IgG Fc BP-HRP Bundle | sc-539094 | 200 µg Ab; 10 µg BP | $354.00 | |||
Acidic Cytokeratin Antibody (AE1): m-IgG1 BP-HRP Bundle | sc-541254 | 200 µg Ab; 20 µg BP | $354.00 | |||
Acidic Cytokeratin Antibody (AE1) FITC | sc-58719 FITC | 200 µg/ml | $330.00 |