Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (162): sc-65797
- Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (162) is a rat monoclonal IgM provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChRγ of Torpedo origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (162). This work is in progress.
AChRγ Antibody (162) is a rat monoclonal IgM antibody that detects AChRγ in Torpedo species through applications such as western blotting (WB) and immunofluorescence (IF). AChRγ, a 517 amino acid member of the acetylcholine receptor family, is crucial for ligand binding and neuromuscular organogenesis, highlighting AChRγ′s importance in the development and function of the neuromuscular junction. AChRγ is primarily located at the postsynaptic membrane, where AChRγ plays a vital role in synaptic transmission by allowing the flow of ions in response to acetylcholine binding. The proper functioning of AChRγ is essential for muscle contraction and overall motor function, and any mutations in the gene encoding AChRγ can lead to severe developmental disorders, such as Escobar syndrome and a lethal form of multiple pterygium syndrome. Anti-AChRγ antibody (162) provides a reliable tool for researchers studying the dynamics of neuromuscular transmission and the underlying mechanisms of related pathologies, making anti-AChRγ antibody (162) an invaluable resource in the field of neurobiology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (162) | sc-65797 | 200 µg/ml | $316.00 |