Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (132): sc-65796
- Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (132) is a rat monoclonal IgG1 provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChR of Torpedo origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (132). This work is in progress.
AChRγ Antibody (132) is a rat monoclonal IgG1 antibody that detects AChRγ in Torpedo species through applications such as western blotting (WB) and immunofluorescence (IF). AChRγ is a crucial member of the acetylcholine receptor family, consisting of 517 amino acids, and plays a significant role in ligand binding and neuromuscular organogenesis. AChRγ is primarily located at the postsynaptic membrane of the neuromuscular junction, where AChRγ facilitates signal transmission by binding acetylcholine, which is essential for muscle contraction and overall neuromuscular function. Proper functioning of AChRγ is vital, as mutations in the gene encoding AChRγ can lead to severe developmental disorders, including Escobar syndrome and a lethal form of multiple pterygium syndrome. Anti-AChRγ antibody (132) enables researchers to gain insights into the molecular mechanisms underlying these conditions and explore the broader implications of acetylcholine signaling in neuromuscular health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor gamma/CHRNG Antibody (132) | sc-65796 | 200 µg/ml | $322.00 |