Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (118): sc-65787
- Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (118) is a rat monoclonal IgG1, cited in 1 publications, provided at 200 µg/ml
- raised against denatured, purified AChR of Torpedo origin
- recommended for detection of nicotinic AChRβ1 of mouse, rat, human, bovine and Torpedo origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (118). This work is in progress.
AChRβ1 Antibody (118) is a rat monoclonal IgG1 antibody that detects AChRβ1 in mouse, rat, human, bovine, and Torpedo by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). AChRβ1, also known as CHRNB, CMS1D, CMS2A, SCCMS, or CHRNB1, is a crucial 501 amino acid protein that plays a significant role in the ligand-gated ion channel receptor family, essential for fast synaptic transmission in the nervous system. AChRβ1 is primarily located at the postsynaptic membrane of the neuromuscular junction, where AChRβ1 binds acetylcholine, facilitating ion movement through its transmembrane aqueous pore. Proper functioning of AChRβ1 is vital for muscle contraction and overall neuromuscular function, as defects in the gene encoding AChRβ1 can lead to congenital myasthenic syndrome slow-channel type (SCCMS), a condition characterized by muscle weakness affecting various muscle groups, including those responsible for eye movement and facial expressions. Anti-AChRβ1 antibody (118) serves as an invaluable tool for researchers studying neuromuscular disorders and synaptic transmission mechanisms, providing insights into AChRβ1′s structure and interactions with other proteins in signaling pathways that govern muscle activity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor beta 1/CHRNB1 Antibody (118) | sc-65787 | 200 µg/ml | $322.00 |