Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (311): sc-65870
- Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (311) is a rat monoclonal IgG2b provided at 200 µg/ml
- raised against bacterially expressed large cytoplasmic domain fragment of chicken origin
- recommended for detection of nicotinic AChRα8 of avian origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (311). This work is in progress.
AChRα8 Antibody (311) is a rat monoclonal IgG2b antibody that detects AChRα8 in avian species through applications such as western blotting (WB) and immunofluorescence (IF). AChRα8 is a crucial component of the ligand-gated ion channel receptor family, specifically functioning as a multi-pass membrane protein composed of 456 amino acids. AChRα8 plays a vital role in synaptic transmission by forming a transmembrane aqueous pore that allows ions to flow in response to neurotransmitter binding, particularly at the neuromuscular junction. AChRα8 is essential for proper functioning of the neuromuscular system, facilitating rapid transmission of signals necessary for muscle contraction. Additionally, AChRα8 undergoes various post-translational modifications, which can influence activity and interaction with other proteins, thereby affecting synaptic plasticity and overall neuronal communication. AChRα8′s ability to interact with specific proteins, such as scaffolding proteins and other receptor subunits, further underscores its importance in maintaining the integrity and functionality of synaptic connections. With unique properties and critical role in neurotransmission, anti-AChRα8 antibody (311) is an invaluable tool for researchers studying avian neuromuscular physiology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (311) | sc-65870 | 200 µg/ml | $316.00 |