Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (310): sc-65869
- Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (310) is a rat monoclonal IgG provided at 200 µg/ml
- raised against a bacterially expressed large cytoplasmic domain fragment of chicken origin
- recommended for detection of nicotinic AChRα8 of avian origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (310). This work is in progress.
AChRα8 Antibody (310) is a rat monoclonal IgG antibody that recognizes AChRα8 in avian species through western blotting (WB) and immunofluorescence (IF). AChRα8 is a crucial component of the ligand-gated ion channel receptor family, functioning as a multi-pass membrane protein composed of 456 amino acids. AChRα8 plays a significant role in neurotransmission by forming a transmembrane aqueous pore that allows ions to flow in response to acetylcholine binding. AChRα8 at the postsynaptic membrane of the neuromuscular junction is vital for muscle contraction and overall motor function, facilitating rapid transmission of signals between nerve cells and muscles. AChRα8 also modulates synaptic plasticity in the central nervous system, contributing to learning and memory processes. AChRα8′s dynamic nature and interactions with other proteins in the receptor family underscore its significance in both peripheral and central nervous system signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor alpha 8/CHRNA8 Antibody (310) | sc-65869 | 200 µg/ml | $316.00 |