Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (6): sc-65844
- Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (6) is a rat monoclonal IgG1, cited in 1 publications, provided at 200 µg/ml
- raised against AChR of Torpedo origin
- recommended for detection of nicotinic AChRα1 of Torpedo and Electrophorus origin by WB and IF
- See Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 (153): sc-65829 for Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (6). This work is in progress.
AChRα1 Antibody (6) is a rat monoclonal IgG1 antibody that detects AChRα1 in Torpedo and Electrophorus species through western blotting (WB) and immunofluorescence (IF). AChRα1, also known as ACHRD, CHRNA, CMS2A, FCCMS, SCCMS, or CHRNA1, is a crucial component of the nicotinic acetylcholine receptor family, functioning as a multi-pass membrane protein composed of 482 amino acids. AChRα1 plays a vital role in neuromuscular transmission by forming a transmembrane aqueous pore that allows ions to flow in response to acetylcholine binding, which is essential for muscle contraction and overall neuromuscular function. AChRα1 exists in two alternatively spliced isoforms, with isoform 1 being specifically expressed in skeletal muscle, while isoform 2 is widely distributed across various tissues, including the brain, heart, kidney, liver, lung, and thymus. The presence of these isoforms highlights AChRα1′s diverse functional roles in different physiological contexts, making anti-AChRα1 antibody (6) an invaluable tool for researchers exploring neurotransmission and receptor function in both normal and pathological states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (6) | sc-65844 | 200 µg/ml | $322.00 |