Date published: 2026-1-9

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Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (210): sc-58603

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Datasheets
  • Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (210) is a rat monoclonal IgG1 provided at 200 µg/ml
  • raised against full length muscle AChR of mouse
  • recommended for detection of neuronal native AChRα3 and AChRα5 of mouse, rat, human, bovine and canine origin by WB, IP, IF and ELISA; also recommended for detection of denatured AChRα1; may cross-react with human AChRβ3
  • See Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 (153): sc-65829 for Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (210). This work is in progress.

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    AChRα1/3/5 Antibody (210) is a rat monoclonal IgG1 antibody that detects AChRα1/3/5 in mouse, rat, human, bovine, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AChRα1/3/5 is a critical component of the nicotinic acetylcholine receptor family, which plays a vital role in fast synaptic transmission by mediating the flow of ions across the cell membrane in response to acetylcholine binding. These receptors are predominantly located at the postsynaptic membrane of the neuromuscular junction and in the central nervous system, where they facilitate rapid communication between neurons and muscle cells. The proper functioning of AChRα1/3/5 is essential for muscle contraction and neurotransmission, and any mutations in the genes encoding these receptors can lead to severe neurological disorders and increased susceptibility to diseases such as lung cancer. Anti-AChRα1/3/5 antibody (210) provides reliable detection and characterization of these receptors, enabling researchers to explore their roles in various physiological and pathological processes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (210)

    sc-58603
    200 µg/ml
    $322.00

    What is the recommended storage condition for AChRα1/3/5 (210): sc-58603?

    Asked by: cjMara
    Thank you for your question. We recommend storing the antibody at 4° C.
    Answered by: Technical Support
    Date published: 2017-03-27
    • y_2025, m_12, d_30, h_8CST
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    Rated 5 out of 5 by from Excellent -Gold standard alpha1 ACHR antibodyWe have validated it for: Flow cytometry conformational-correct membrane bound cell-based assays Indirect immunofluorescence of conformational-correct membrane bound cell-based assays Luminescent labelling of conformational-correct membrane bound cell-based assays Extremely stable; we have observational data for experimental reproducibility > 24 months when kept at 4C.
    Date published: 2025-11-16
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    Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (210) is rated 3.5 out of 5 by 2.
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