Date published: 2026-6-23

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Acetylene-PEG5-NHS ester (CAS 1393330-40-9)

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Alternate Names:
Alkyne-PEG5-N-hydroxysuccinimidyl ester; Propargyl-PEG5-NHS ester
Application:
Acetylene-PEG5-NHS ester is an amine reactive crosslinker for incorporation of a terminal alkyne
CAS Number:
1393330-40-9
Molecular Weight:
401.41
Molecular Formula:
C18H27NO9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acetylene-PEG5-NHS ester is a heterobifunctional crosslinker that enables the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetylene-PEG5-NHS ester, 10 mg

sc-397269
10 mg
$77.00

Acetylene-PEG5-NHS ester, 25 mg

sc-397269A
25 mg
$163.00