Azide-Alkyne Click Crosslinkers
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Propargyl-succinimidyl-ester | 1174157-65-3 | sc-397263 sc-397263A | 50 mg 250 mg | $100.00 $320.00 | ||
Propargyl-succinimidyl-ester is a versatile reagent that facilitates the azide-alkyne click reaction through its reactive alkyne moiety. This compound exhibits rapid reaction kinetics, enabling efficient formation of stable triazole linkages. Its succinimidyl group enhances nucleophilic attack, promoting selective conjugation with azides. The compound's unique steric and electronic properties allow for precise control over reaction conditions, making it a valuable tool in synthetic chemistry for creating complex molecular architectures. | ||||||
DBCO-maleimide | sc-397264 sc-397264A | 1 mg 5 mg | $17.00 $81.00 | |||
DBCO-maleimide is a specialized compound that excels in the azide-alkyne click reaction, characterized by its unique reactivity profile. The strained cyclooctyne structure of DBCO promotes rapid and selective cycloaddition with azides, resulting in stable triazole formations. Its maleimide functionality further enhances thiol reactivity, allowing for dual conjugation strategies. This compound's distinct electronic properties and steric effects facilitate precise control over reaction dynamics, making it an essential reagent in advanced synthetic applications. | ||||||
DBCO-PEG4-maleimide | 1480516-75-3 | sc-397265 sc-397265A sc-397265B | 1 mg 5 mg 50 mg | $46.00 $117.00 $348.00 | ||
DBCO-PEG4-maleimide is a versatile reagent that showcases remarkable efficiency in the azide-alkyne click reaction. Its PEG4 linker enhances solubility and biocompatibility, while the DBCO moiety ensures rapid cycloaddition with azides, yielding stable products. The maleimide group introduces a unique thiol-reactive site, enabling diverse conjugation pathways. This compound's tunable reactivity and favorable kinetics make it ideal for complex molecular assembly and bioconjugation strategies. | ||||||
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester | 1353016-71-3 | sc-397268 sc-397268A | 1 mg 5 mg | $26.00 $79.00 | ||
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester is a highly reactive compound that facilitates the azide-alkyne click reaction through its unique dibenzocyclooctyne structure. This compound exhibits rapid reaction kinetics, allowing for efficient cycloaddition with azides. The N-hydroxysuccinimidyl ester moiety enhances its reactivity towards amines, promoting selective conjugation. Its distinct molecular architecture enables precise control over reaction conditions, making it suitable for intricate chemical modifications. | ||||||
Acetylene-PEG5-NHS ester | 1393330-40-9 | sc-397269 sc-397269A | 10 mg 25 mg | $77.00 $163.00 | ||
Acetylene-PEG5-NHS ester is a versatile compound that excels in the azide-alkyne click reaction due to its unique polyethylene glycol (PEG) linker, which enhances solubility and biocompatibility. The NHS ester group provides a highly reactive site for amine coupling, facilitating efficient conjugation. Its linear structure allows for flexible molecular interactions, promoting rapid reaction kinetics and enabling precise control over functionalization in diverse chemical environments. | ||||||
2-{4-[(Dimethylamino)methyl]-1,2,3-triazol-1-yl}cyclohexan-1-ol | 1817837-32-3 | sc-506318 | 100 mg | $66.00 | ||
2-{4-[(Dimethylamino)methyl]-1,2,3-triazol-1-yl}cyclohexan-1-ol exhibits unique reactivity in azide-alkyne click chemistry, where its triazole moiety acts as a stabilizing scaffold for transition states. The presence of the dimethylamino group enhances solubility and facilitates intramolecular interactions, leading to efficient cycloaddition pathways. Additionally, the cyclohexanol structure provides steric hindrance that fine-tunes selectivity, optimizing product formation in diverse synthetic applications. | ||||||
Alkyne-PEG4-maleimide | sc-397271 sc-397271A | 10 mg 25 mg | $55.00 $127.00 | |||
Alkyne-PEG4-maleimide is a specialized compound that showcases remarkable reactivity in the azide-alkyne click reaction, driven by its maleimide moiety, which selectively forms stable thioether bonds with thiols. The PEG4 linker enhances solubility and reduces steric hindrance, allowing for efficient molecular interactions. This compound's unique structure promotes rapid reaction kinetics, enabling precise and controlled conjugation in various chemical contexts, making it a powerful tool for bioconjugation applications. | ||||||
DBCO-Amine | 1255942-06-3 | sc-506546 sc-506546A sc-506546B | 100 mg 250 mg 1 g | $422.00 $1055.00 $2678.00 | ||
DBCO-Amine is a highly reactive compound that excels in azide-alkyne cycloaddition reactions, showcasing remarkable selectivity and efficiency. Its unique bicyclic structure promotes a rapid and specific formation of triazole linkages, minimizing side reactions. The compound's hydrophilic and lipophilic characteristics enable it to engage in diverse molecular interactions, making it suitable for various synthetic pathways. Additionally, its stability under ambient conditions enhances its utility in complex chemical systems. | ||||||
DBCO-PEG(4)-NH2 | 1255942-08-5 | sc-506569 | 25 mg | $332.00 | ||
DBCO-PEG(4)-NH2 exhibits remarkable reactivity through its efficient participation in azide-alkyne click chemistry, driven by the inherent strain of the DBCO moiety. The PEG chain imparts flexibility and hydrophilicity, promoting enhanced solvation and interaction with various substrates. Its amine functionality serves as a versatile anchor for subsequent modifications, allowing for tailored properties and improved kinetics in conjugation reactions, thus broadening its applicability in synthetic chemistry. | ||||||