ABCF1 Antibody (H-3): sc-377185
- ABCF1 Antibody (H-3) is a mouse monoclonal IgG1 κ ABCF1 antibody provided at 200 µg/ml
- raised against amino acids 524-658 mapping within an internal region of ABCF1 of human origin
- ABCF1 Antibody (H-3) is recommended for detection of ABCF1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and bovine and porcine
- Anti-ABCF1 Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ABCF1 Antibody (H-3). This work is in progress.
ABCF1 Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects ABCF1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ABCF1 (H-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ABCF1 protein, also known as ATP-binding cassette sub-family F member 1, is a crucial 845 amino acid protein encoded by the human gene ABCF1, which plays a significant role in mRNA translation through interaction with eukaryotic initiation factor 2 (eIF2) and is associated with ribosomes. Notably, ABCF1 is unique among ABC transporters as ABCF1 lacks typical transmembrane domains, which are characteristic of most members of the ABC transporter family. ABCF1 is ubiquitously expressed and can be induced by tumor necrosis factor (TNF), highlighting ABCF1′s importance in cellular responses to stress. Furthermore, upon DNA damage, ABCF1 undergoes phosphorylation by either ataxia-telangiectasia mutated (ATM) or ATM and Rad3-related (ATR) kinases, which may influence ABCF1′s function in cellular repair mechanisms. The diverse applications of anti-ABCF1 antibody (H-3) make ABCF1 (H-3) antibody an essential tool for researchers studying the intricate roles of ABCF1 in cellular processes and potential implications in disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ABCF1 Antibody (H-3) References:
- An inventory of the human ABC proteins. | Klein, I., et al. 1999. Biochim Biophys Acta. 1461: 237-62. PMID: 10581359
- ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients. | Shichijo, S., et al. 2005. Oncol Rep. 13: 907-13. PMID: 15809757
- Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis. | Ota, M., et al. 2007. Immunogenetics. 59: 45-52. PMID: 17119950
- ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. | Matsuoka, S., et al. 2007. Science. 316: 1160-6. PMID: 17525332
- Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity. | Chloupková, M., et al. 2007. Biochemistry. 46: 7992-8003. PMID: 17569508
- Mapping ATP-binding cassette transporter gene expression profiles in melanocytes and melanoma cells. | Heimerl, S., et al. 2007. Melanoma Res. 17: 265-73. PMID: 17885581
- The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2. | Paytubi, S., et al. 2008. Biochem J. 409: 223-31. PMID: 17894550
- ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes. | Richard, M., et al. 1998. Genomics. 53: 137-45. PMID: 9790762
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ABCF1 Antibody (H-3) | sc-377185 | 200 µg/ml | $316.00 | |||
ABCF1 Antibody (H-3) AC | sc-377185 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ABCF1 Antibody (H-3) HRP | sc-377185 HRP | 200 µg/ml | $316.00 | |||
ABCF1 Antibody (H-3) FITC | sc-377185 FITC | 200 µg/ml | $330.00 | |||
ABCF1 Antibody (H-3) PE | sc-377185 PE | 200 µg/ml | $343.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 488 | sc-377185 AF488 | 200 µg/ml | $357.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 546 | sc-377185 AF546 | 200 µg/ml | $357.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 594 | sc-377185 AF594 | 200 µg/ml | $357.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 647 | sc-377185 AF647 | 200 µg/ml | $357.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 680 | sc-377185 AF680 | 200 µg/ml | $357.00 | |||
ABCF1 Antibody (H-3) Alexa Fluor® 790 | sc-377185 AF790 | 200 µg/ml | $357.00 |