Molecular structure of 6,7-Dinitroquinoxaline-2,3-dione (DNQX), CAS Number: 2379-57-9
6,7-Dinitroquinoxaline-2,3-dione (DNQX) (CAS 2379-57-9)
See product citations (6)
Alternate Names:
FG 9041
Application:
6,7-Dinitroquinoxaline-2,3-dione (DNQX) is a non-NMDA receptor complex antagonist
CAS Number:
2379-57-9
Purity:
≥98%
Molecular Weight:
252.14
Molecular Formula:
C8H4N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6,7-Dinitroquinoxaline-2,3-dione (DNQX) is a non-N-methyl-D-aspartate (non-NMDA) receptor complex antagonist. The compound may act to attenuate JNK3 activation and has been shown not to stimulate a robust long-term potentiation in hippocampul studies. 6,7-Dinitroquinoxaline-2,3-dione (DNQX) is an inhibitor of GluR.
6,7-Dinitroquinoxaline-2,3-dione (DNQX) (CAS 2379-57-9) References
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- Ammonia-induced extracellular accumulation of taurine in the rat striatum in vivo: role of ionotropic glutamate receptors. | Zielińska, M., et al. 2002. Neurochem Res. 27: 37-42. PMID: 11926274
- Excitatory amino acid receptor antagonists and electroacupuncture synergetically inhibit carrageenan-induced behavioral hyperalgesia and spinal fos expression in rats. | Zhang, YQ., et al. 2002. Pain. 99: 525-535. PMID: 12406529
- Quisqualate neurotoxicity in rat cortical cultures: pharmacology and mechanisms. | Zinkand, WC., et al. 1992. Eur J Pharmacol. 212: 129-36. PMID: 1534767
- Heterogeneous expression and regulation of hippocampal prostaglandin E2 receptors. | Zhu, P., et al. 2005. J Neurosci Res. 81: 817-26. PMID: 16041798
- Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors. II. Behavioral effects of selective glutamate receptor antagonists AP-5, CNQX, and DNQX. | Georgescu, M. and Pfaus, JG. 2006. Pharmacol Biochem Behav. 83: 333-41. PMID: 16580057
- NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus. | Zhu, L., et al. 2008. Epilepsy Res. 79: 201-12. PMID: 18394864
- Selective excitatory actions of DNQX and CNQX in rat thalamic neurons. | Lee, SH., et al. 2010. J Neurophysiol. 103: 1728-34. PMID: 20107128
- Contributions of quisqualate and NMDA receptors to the induction and expression of LTP. | Muller, D., et al. 1988. Science. 242: 1694-7. PMID: 2904701
- Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons. | Zhao, X., et al. 2020. Oxid Med Cell Longev. 2020: 5173184. PMID: 32849999
- Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced responses in Xenopus oocytes expressing chick brain glutamate receptors. | Zhou, N., et al. 1993. Neuropharmacology. 32: 767-75. PMID: 7692340
- Neuronal circuits associated with the output of the dorsal cochlear nucleus through fusiform cells. | Zhang, S. and Oertel, D. 1994. J Neurophysiol. 71: 914-30. PMID: 8201432
- Glutamate receptor subtypes mediate excitatory synaptic responses of rat lateral parabrachial neurons. | Zidichouski, JA., et al. 1996. Am J Physiol. 270: H1557-67. PMID: 8928860
Inhibitor of:
GluR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6,7-Dinitroquinoxaline-2,3-dione (DNQX), 10 mg | sc-200444 | 10 mg | $62.00 | |||
6,7-Dinitroquinoxaline-2,3-dione (DNQX), 50 mg | sc-200444A | 50 mg | $133.00 |