Molecular structure of 5(S)-HETE-d8, CAS Number: 330796-62-8
5(S)-HETE-d8 (CAS 330796-62-8)
Alternate Names:
5S- hydroxy- 6E,8Z,11Z,14Z- eicosatetraenoic- 5,6,8,9,11,12,14,15- d8 acid
Application:
5(S)-HETE-d8 is an internal standard for the quantification of 5(S)-HETE by GC or LC-mass spectrometry
CAS Number:
330796-62-8
Molecular Weight:
328.52
Molecular Formula:
C20H24D8O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5(S)-HETE-d8 contains eight deuterium atoms at positons 5, 6, 8, 9, 11, 12, 14, and 15. It is used as an internal standard for the quantification of 5(S)-HETE by GC- or LC-mass spectrometry (MS). 5(S)-HETE is produced by the action of 5-lipoxygenase on arachidonic acid to give 5(S)-HpETE, followed by reduction of hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes(1). When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4(2,3).
5(S)-HETE-d8 (CAS 330796-62-8) References
1 Schwenk, U., Schröder, J. 5-oxo-Eicosanoids are potent eosinophil chemotactic factors. J Biol Chem 270 15029-15036 (1994). 2 Powell, W.S., Gravelle, F., Gravel, S. Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosaOrdering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5(S)-HETE-d8, 25 µg | sc-221072 | 25 µg | $145.00 | |||
5(S)-HETE-d8, 50 µg | sc-221072A | 50 µg | $368.00 |