5-Chloro-2-(4-nitrophenyl)-3(2H)-isothiazolone (CAS 748777-47-1)

5-Chloro-2-(4-nitrophenyl)-3(2H)-isothiazolone is a chemical compound that belongs to the isothiazolone class, known for its robust biocidal properties due to the presence of a reactive isothiazolone ring which confers the ability to interfere with microbial cell functions. The specific structure of this compound, characterized by the incorporation of a nitrophenyl group at the 4-position and a chlorine atom at the 5-position on the isothiazolone ring, enhances its microbial inhibition potency. The mechanism of action involves the inhibition of essential thiol-containing enzymes in microbial cells, leading to the disruption of cellular metabolism and cell death. This compound is particularly useful in non-medical research settings, such as in studies aimed at controlling biofouling in industrial water systems, where microbial control is crucial to prevent the degradation of materials and efficiency. The effectiveness of 5-Chloro-2-(4-nitrophenyl)-3(2H)-isothiazolone in various environmental conditions, including its stability and degradation kinetics, is also a significant area of study, helping to evaluate its environmental impact and suitability for use in a range of industrial applications. Additionally, its role in the development of new biocidal formulations offers a promising avenue for enhancing the efficacy of microbial control strategies in non-clinical environments.