Molecular structure of 2-Pyridylethylamine dihydrochloride, CAS Number: 3343-39-3
2-Pyridylethylamine dihydrochloride (CAS 3343-39-3)
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Alternate Names:
2-Pyridineethanamine dihydrochloride
Application:
2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction
CAS Number:
3343-39-3
Purity:
≥98%
Molecular Weight:
195.09
Molecular Formula:
C7H10N2•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction. 2-Pyridylethylamine dihydrochloride (2-PEA-DHC) is an organic compound characterized by a pyridine ring and an ethylamine side chain, existing as a hydrochloride salt. It manifests as a white crystalline solid, melting at around 150°C, and demonstrates solubility in water and alcohols.
2-Pyridylethylamine dihydrochloride (CAS 3343-39-3) References
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- Histamine H1 receptors are involved in mouse nasal allergic responses: a demonstration with H1 receptor-deficient mice. | Kayasuga, R., et al. 2002. Int Immunopharmacol. 2: 745-50. PMID: 12095164
- Effect of histamine and histamine analogues on human isolated myometrial strips. | Martínez-Mir, MI., et al. 1992. Br J Pharmacol. 107: 528-31. PMID: 1358393
- Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction. | Forward, NA., et al. 2009. J Immunol. 183: 3014-22. PMID: 19667094
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- Naloxone antagonizes a central histaminergic stimulation of corticosterone secretion in rats. | Gadek-Michalska, A. and Bugajski, J. 1988. Agents Actions. 23: 254-6. PMID: 2839961
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- Histamine H1-receptors mediate phosphoinositide and calcium response in cultured smooth muscle cells--interaction with cicletanine (CIC). | Lonchampt, MO., et al. 1988. Agents Actions. 24: 255-60. PMID: 2845743
- Histamine augments collagen content via H1 receptor stimulation in cultures of myofibroblasts taken from wound granulation tissue. | Wolak, M., et al. 2021. Mol Cell Biochem. 476: 1083-1092. PMID: 33230787
- A Novel Potent Sleep-Promoting Effect of Turmeric: Turmeric Increases Non-Rapid Eye Movement Sleep in Mice Via Histamine H1 Receptor Blockade. | Um, MY., et al. 2021. Mol Nutr Food Res. 65: e2100100. PMID: 34003596
- Histamine is involved in the regulation of collagen content in cultured heart myofibroblasts via H2, H3 and H4 histamine receptors. | Piera, L., et al. 2021. Biomed Rep. 15: 71. PMID: 34276989
- Histamine/H1 receptor signaling in the parafacial region increases activity of chemosensitive neurons and respiratory activity in rats. | Sobrinho, CR., et al. 2022. J Neurophysiol. 128: 218-228. PMID: 35704395
- Mechanisms involved in the vasorelaxing influence of histamine on isolated human subcutaneous resistance arteries. | Van de Voorde, J., et al. 1998. Eur J Pharmacol. 349: 61-6. PMID: 9669497
Activator of:
Histamine H1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Pyridylethylamine dihydrochloride, 50 mg | sc-203467 | 50 mg | $273.00 |