17-β Estradiol 6 Antibody (6F92): sc-69960
- 17-β Estradiol 6 Antibody (6F92) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against 17-β Estradiol 6 of human origin conjugated to BSA
- recommended for detection of 17-β Estradiol 6 of human origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for 17-β Estradiol 6 Antibody (6F92). This work is in progress.
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17-β Estradiol 6 Antibody (6F92) is a mouse monoclonal IgG1 antibody that detects 17-β Estradiol in human samples through enzyme-linked immunosorbent assay (ELISA). 17-β Estradiol is a crucial mammalian estrogenic hormone primarily produced in the ovaries, placenta, testis, and potentially the adrenal cortex, playing a vital role in various physiological processes. This hormone is synthesized from precursors such as acetate, cholesterol, progesterone, and testosterone, and is essential for the regulation of reproductive functions and the development of secondary sex characteristics. Beyond reproductive roles, 17-β Estradiol significantly influences bone growth, brain development, and the modulation of intracellular calcium levels and second messenger molecules. Research has shown that 17-β Estradiol exhibits protective effects on different cell types following trauma-hemorrhage, enhancing circulation through the relaxation of the aorta and exerting anti-apoptotic effects on endothelial cells. Additionally, 17-β Estradiol has been implicated in the attenuation of hydrogen peroxide-induced apoptosis via estrogen receptor-dependent activation of caspases in rat endothelial cells, highlighting its importance in cellular survival mechanisms. Anti-17-β Estradiol antibody (6F92) serves as an invaluable tool for researchers investigating the multifaceted roles of this hormone in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17-β Estradiol 6 Antibody (6F92) | sc-69960 | 100 µg/ml | $316.00 |