Date published: 2025-9-9

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TLR4 항체 (MTS510): sc-13591

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데이터 시트
  • TLR4 항체 MTS510 는 랫드 monoclonal IgG2a, 53간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • Toll-like receptor 4 (TLR4)/MD-2 complex of mouse origin에 대해 제기됨
  • 안티-TLR4 항체 (MTS510)는 IP, IF and FCM으로 mouse, rat and human유래의 TLR4/MD-2 complex 를 감지하는 데에 추천한다.
  • 항-TLR4 항체(MTS510)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • NAP-2 억제용으로 아지드가 없는 제품도 제공됨, sc-73636 L, 200 µg/0.1 ml
  • TLR4 (MTS510): sc-13591무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • 현재 TLR4 항체(MTS510)에 대해 선호하는 2차 검출 시약의 식별을 아직 완료하지 못했습니다. 이 작업은 진행 중입니다.

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TLR4 항체(MTS510)는 면역침전법(IP), 면역형광법(IF), 유세포분석법(FCM)을 통해 쥐, 쥐, 인간에서 유래된 TLR4/MD-2 복합체를 검출하는 쥐 단일클론 IgG2a 항체입니다. TLR4(MTS510) 항체는 비접합 형태와 아가로스, 호스래디시 퍼옥시다아제(HRP), 피코에리트린(PE), 플루오레세인 이소티오시아네이트(FITC), 다중 알렉사 플루오르® 접합체를 포함한 다양한 접합 형태로 제공됩니다. TLR4는 그람 음성균의 리포폴리사카라이드(LPS)를 인식함으로써 면역계에서 중요한 역할을 수행합니다. 이 물질은 핵 인자 kappa 경쇄 강화제(NFkB)의 활성화와 그에 따른 전염증성 사이토카인의 생산을 유발하는 신호 전달 경로를 촉발합니다. 이 기능은 효과적인 면역 반응을 시작하고 감염 동안 항상성을 유지하는 데 필수적입니다. TLR4는 주로 대식세포와 수지상 세포와 같은 면역 세포의 세포 표면에 위치하며, 이 세포 표면에서 TLR4가 병원체 탐지를 위한 감시자 역할을 합니다. TLR4의 적절한 기능은 선천성 면역 반응에 필수적이며, 조절 장애는 만성 염증성 질환이나 면역 반응 장애로 이어질 수 있습니다. TLR4(MTS510) 단일 클론 항체는 면역 활성화의 메커니즘과 다양한 질병에서 TLR의 역할을 연구하는 연구자들에게 매우 중요한 도구입니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

LI-COR®와 Odyssey®는 LI-COR Biosciences의 등록 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

TLR4 항체 (MTS510)

sc-13591
200 µg/ml
$316.00

TLR4 항체 (MTS510) L

sc-13591 L
200 µg/0.1 ml
$316.00

TLR4 항체 (MTS510) AC

sc-13591 AC
500 µg/ml, 25% agarose
$416.00

TLR4 항체 (MTS510) HRP

sc-13591 HRP
200 µg/ml
$316.00

TLR4 항체 (MTS510) FITC

sc-13591 FITC
200 µg/ml
$330.00

TLR4 항체 (MTS510) PE

sc-13591 PE
200 µg/ml
$343.00

TLR4 항체 (MTS510) Alexa Fluor® 488

sc-13591 AF488
200 µg/ml
$357.00

TLR4 항체 (MTS510) Alexa Fluor® 546

sc-13591 AF546
200 µg/ml
$357.00

TLR4 항체 (MTS510) Alexa Fluor® 594

sc-13591 AF594
200 µg/ml
$357.00

TLR4 항체 (MTS510) Alexa Fluor® 647

sc-13591 AF647
200 µg/ml
$357.00

TLR4 항체 (MTS510) Alexa Fluor® 680

sc-13591 AF680
200 µg/ml
$357.00

TLR4 항체 (MTS510) Alexa Fluor® 790

sc-13591 AF790
200 µg/ml
$357.00

I would like to know the endotoxin level for this antibody as we are interested in using it for in-vivo blockade experiment in mice

Asked by: Donnest
Thank you for contacting Santa Cruz Biotechnology. For more details please contact technical service by calling 800-457-3801.
Answered by: BlakeJ
Date published: 2025-01-30

Do you know if the anti TLR4 clone MTS510 works (IHC) on chicken tissues?? Or do you have a clone against TLR4 who does works onchicken? I read an article (ansari 2017, bursal atrophy, TLR4) he used an antibody of santa cruz that works in chicken,

Asked by: rob z
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-10-12

How much is the molecular weight of TLR4 Antibody (MTS510)(sc-13591)? Is the unit of this regent 1ml?

Asked by: Yuanyuan JI
Thank you for your question. The expected molecular weight for TLR4 is 95kDa (120kDa if glycosylated). The product is provided as 200µg in 1ml. Please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com if you have any further questions.
Answered by: Tech Service
Date published: 2018-01-08

What is the epitope recognized by sc-13591: TLR4 (MTS510)?

Asked by: cjMara
LR4 Antibody (MTS510) is a rat monoclonal raised against Toll-like receptor 4 (TLR4)/MD-2 complex of mouse origin. The exact epitope has not been determined.
Answered by: Technical Support 8
Date published: 2017-01-11

What negative control should be used when using the conjugated version of TLR4 (MTS510) monoclonal antibody in flow cytometry?

Asked by: cjMara
Thank you for your inquiry. We recommend using the isotype specific normal rat IgG conjugated to the same fluorophore. For example, if you are using sc-13591 PE, then you would want to use normal rat IgG2a PE, sc-2872.
Answered by: Technical Support 8
Date published: 2017-01-11
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Rated 3 out of 5 by from This antibody works with western blottingThis antibody works with western blotting with SAS cells lysate.
Date published: 2020-06-12
Rated 5 out of 5 by from Good antibodyWorks nicely on mouse and human brain sections (PFA-fixed)
Date published: 2018-06-13
Rated 5 out of 5 by from Good for flowGood TLR4 antibody for flow cytometry. Direct conjugates available to bypass secondary antibody. "L" form is available as azide-free for inhibition of LPS-induced cytokine production.
Date published: 2017-01-23
Rated 5 out of 5 by from Great FCM and IHCNice product but two alternative TLR4 Monoclonals also from scbt have outstanding data for broader base of applications
Date published: 2017-01-15
Rated 5 out of 5 by from Good results in CoIP with mouse cellsGood results in CoIP with mouse cells -SCBT Publication Review
Date published: 2015-04-15
Rated 5 out of 5 by from Excellent for IHC with mouse kidneyExcellent for IHC with mouse kidney -SCBT Publication Review
Date published: 2015-02-03
Rated 4 out of 5 by from PE conjugate works very well in FlowPE conjugate works very well in Flow -SCBT QC
Date published: 2013-08-03
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TLR4 항체 (MTS510) is rated 4.6 out of 5 by 7.
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