Date published: 2025-9-9

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PGC-1α 항체 (D-5): sc-518025

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  • PGC1a 항체 D-5 는 마우스 monoclonal IgG2a κ PGC1a 항체, 125간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • 아미노 산1-300 mapping near the N-terminus of PGC-1α of human 의하고 기원한다
  • PGC1a 항체 (D-5)는 WB, IP, IF, IHC(P) and ELISA으로 mouse, rat and human유래의 PGC-1α 를 감지하는 데에 추천한다.
  • 항-PGC1a 항체(D-5)는 IP용 agarose와 결합되어 이용 가능하며, WB, IHC(P), ELISA용 HRP와 결합되어 이용 가능하며, IF, IHC(P), FCM용 phycoerythrin 또는 FITC와 결합되어 이용 가능합니다.
  • WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
  • WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
  • PGC1a (D-5): sc-518025무료10 µg 샘플을 신청하려면 기술지원팀 (또는 로컬 디스트리뷰터)에 연락주세요.
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 는 PGC1a 항체 (D-5) 가 WB and IHC(P) 에 응용될 때 우선으로 사용하는 이차 항체 검사 시약입니다.이 시약은PGC1a 항체(D-5) 와 세트로 제공드립니다. (아래의 주문 정보를 참고해 주시길 바랍니다).

빠른 링크

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PGC-1α 항체(D-5)는 N-말단 근처의 아미노산 1-300을 표적으로 삼아 쥐, 쥐, 인간에서 유래한 PGC-1α 단백질을 인식하도록 설계된 쥐 단일 클론 IgG2a 카파 경쇄 항체입니다. PGC-1α, 또는 퍼옥시좀 증식자 활성화 수용체 감마 코액티베이터 1-알파는 에너지 대사, 미토콘드리아 생성과 적응성 열생성에 관여하는 유전자의 조절을 조율하는 핵심적인 핵 전사 코액티베이터입니다. 주로 핵 내에 위치한 PGC-1α의 핵 내 존재는 매우 중요합니다. PGC-1α는 다양한 전사 인자와 직접 상호 작용할 수 있게 해줌으로써 세포 에너지 요구와 대사 스트레스에 대한 반응으로 유전자 발현을 정밀하게 제어할 수 있게 해줍니다. 이러한 전략적 국소화는 PGC-1α가 에너지 항상성을 유지하고 미토콘드리아 기능을 지원하는 세포 반응을 효과적으로 조정할 수 있도록 합니다. 또한, PGC-1α는 인산화, 아세틸화, 메틸화, 유비퀴틴화를 포함한 광범위한 번역 후 변형을 거치는데, 이러한 변형은 활동, 안정성, 다른 단백질과의 상호작용을 조절하는 데 필수적입니다. 이러한 변형은 PGC-1α가 다양한 세포 신호와 환경 자극에 동적으로 반응할 수 있도록 하여 대사 경로의 유연하고 효율적인 조절을 가능하게 합니다. 항-PGC-1α 항체(D-5)는 웨스턴 블롯(WB), 면역침전(IP), 면역형광(IF), 파라핀 포매 섹션 면역조직화학(IHCP), 효소결합 면역흡착 분석(ELISA) 등의 응용 분야에서 강력한 성능을 발휘하는 연구자들에게 없어서는 안 될 도구입니다. 항-PGC-1α 항체(D-5)는 PGC-1α의 다각적인 역할에 대한 세부적인 조사를 용이하게 함으로써, 대사 조절, 미토콘드리아 역학, 다양한 생리적 및 병리학적 과정의 기초가 되는 분자 메커니즘에 대한 고급 연구를 지원함으로써, 세포 에너지 관리 및 게놈 무결성에 대한 이해에 크게 기여합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

Alexa Fluor®는 미국 오리건주 Molecular Probes Inc.의 상표입니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

PGC1a 항체 (D-5)

sc-518025
200 µg/ml
$316.00

PGC1a (D-5): m-IgG Fc BP-HRP 번들

sc-531597
200 µg Ab; 10 µg BP
$354.00

PGC1a (D-5): m-IgGκ BP-HRP 번들

sc-525331
200 µg Ab, 40 µg BP
$354.00

PGC1a (D-5): m-IgG2a BP-HRP 번들

sc-547825
200 µg Ab; 10 µg BP
$354.00

PGC1a 항체 (D-5) AC

sc-518025 AC
500 µg/ml, 25% agarose
$416.00

PGC1a 항체 (D-5) HRP

sc-518025 HRP
200 µg/ml
$316.00

PGC1a 항체 (D-5) FITC

sc-518025 FITC
200 µg/ml
$330.00

PGC1a 항체 (D-5) PE

sc-518025 PE
200 µg/ml
$343.00

PGC1a 항체 (D-5) Alexa Fluor® 488

sc-518025 AF488
200 µg/ml
$357.00

PGC1a 항체 (D-5) Alexa Fluor® 546

sc-518025 AF546
200 µg/ml
$357.00

PGC1a 항체 (D-5) Alexa Fluor® 594

sc-518025 AF594
200 µg/ml
$357.00

PGC1a 항체 (D-5) Alexa Fluor® 647

sc-518025 AF647
200 µg/ml
$357.00

PGC1a 항체 (D-5) Alexa Fluor® 680

sc-518025 AF680
200 µg/ml
$357.00

PGC1a 항체 (D-5) Alexa Fluor® 790

sc-518025 AF790
200 µg/ml
$357.00

Is N-terminal PGC1a 37kd equivalent to the full-length PGC1a 110kd?

Asked by: gaf56876
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Sen Li
Date published: 2024-04-01

Has this antibody been validated for the application in Flow cytometry analysis ? (especially for mouse samples)

Asked by: 210715
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-23

I am also interested in PGC1a sc-518028 antibody for use in Chromatin Immunoprecipitation and Immunofluorescence staining. Can you confirm that this works?

Asked by: Jeff20
Thank you for your question. We have not yet tested this antibody, nor are we aware of any publications citing use of this antibody for Chromatin Immunoprecipitation (ChIP). This antibody is recommended for immunofluorescent staining (IF) and we have published data available on our website now. There are also multiple product citations using this antibody for IF.
Answered by: Technical Support
Date published: 2019-02-10

I have two questions for the antibody.1: What is the exact molecule weight for WB, 130 or 100KD? 2. Can the antibody be used for flow analysis if I add Alexa Fluor® 488 antibody after incubation?

Asked by: Shaowei
Thank you for your question. The predicted molecular weight for full length PGC-1α1 is ~90 kDa, with the expected observed molecular weight ~115 kDa. This antibody has an N-terminal epitope and we have data detecting a smaller molecular weight isoform, NT-PGC-1α (NT(erminal)-PGC-1α, ~ 37 kDa. The conjugated primary antibody is recommended and warrantied for flow cytometry (FCM), however we are still gathering data to show on our website. Check back for updates!
Answered by: Technical Support
Date published: 2019-02-06

I'm interested in the new PGC-1α Antibody (D-5): sc-518025 for WB and IP in mouse liver lysates. However, in the datasheet I don't see a picture showing an endogenous full lenght PGC1a expression or a sucssefull IP, do you have such data? Thanks,

Asked by: Asael
Thanks for your question. The antibody is recommended for detection of PGC-1α of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA and has been established for these applications. There are two publications that have successfully used PGC-1α Antibody (D-5): sc-518025 in western blot: PMID 30246714 and PMID. So far we have not received any customer feedback for IP with this antibody. 30515824. Please contact technical service for support or to arrange for a free sample of this antibody to see if it is suitable for your application.
Answered by: SCBT Heidelberg Support
Date published: 2019-02-10

你好,请问这个抗体可以申请免费的试用装吗?

Asked by: Alisen
感谢您的提问。关于试用装的申请,欢迎通过:电话(+86) 021-60936350、邮箱asia@scbio.cn、或选择网页上Live Chat中的“中文支持”,联系我们的技术支持部门。 Thank you for your inquiry. For sample request, please contact our Asian Technical Service team at (+86) 021-60936350 or asia@scbio.cn or by live chat on our website.
Answered by: Technical Support 15
Date published: 2018-05-02
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Rated 5 out of 5 by from 抗体质量好我买过很多支这个产家的抗体,质量很好,效果稳定,特异性强,趋势明显,很多在其他产家找不到的抗体都能在这里找到,性价比高
Date published: 2024-01-18
Rated 5 out of 5 by from Well published monoclonal antibodyThis antibody detects the NT-PGC-1α form consistently in Western Blot and is highly published. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from GoodTested in mouse kidney extracts for wb and obtained good results
Date published: 2020-12-03
Rated 2 out of 5 by from debolequesto anticorpo dà un segnale specifico, ma debole
Date published: 2020-10-16
Rated 4 out of 5 by from Worked fine.We used this antibody for WB on lysate from mouse eye with the dilution 1:1000, and it worked fine.
Date published: 2020-10-07
Rated 4 out of 5 by from Worked okay for western blotThis antibody worked okay for western blot with 1:160 dilution. (100 ug protein, rat liver, using the recommended Santa Cruz secondary antibody). There was a faint signal (but detectable) and some background though.
Date published: 2019-07-26
Rated 1 out of 5 by from Not workingNot working Don't waste your time. I bought this instead of discontined SC-13067.
Date published: 2019-06-20
Rated 1 out of 5 by from Doesn't work don't waste time!Dear All, we have tested PGC1-alfa AB from sc and none of them work so far, don't waste time!
Date published: 2018-08-24
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PGC-1α 항체 (D-5) is rated 3.2 out of 5 by 9.
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