Mucin 2/MUC2 Antibody (H-9): sc-515106
- Mucin 2/MUC2 Antibody (H-9) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 4880-5179 mapping at the C-terminus of Mucin 2 of human origin
- Mucin 2/MUC2 Antibody (H-9) is recommended for detection of Mucin 2 of human origin by WB, IP, IF and ELISA
- Anti-Mucin 2/MUC2 Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Mucin 2/MUC2 Antibody (H-9) for WB applications. These reagents are now offered in bundles with Mucin 2/MUC2 Antibody (H-9) (see ordering information below).
Mucin 2 Antibody (H-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects Mucin 2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Mucin 2 antibody (H-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Mucin 2 plays a crucial role in forming a protective barrier in the gastrointestinal tract, where goblet cells secrete Mucin 2 to create a gel-like mucus layer that traps pathogens and facilitates food passage. This function is vital for maintaining gut health and preventing infections, as well as playing a role in the immune response. Mucin 2′s structure is characterized by a high degree of glycosylation and a variable number of tandem repeats, which contribute to Mucin 2′s ability to form viscous gels. Mucin 2 expression is often altered in colonic tumors and cancerous tissues, making Mucin 2 a significant marker for research and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Mucin 2/MUC2 Antibody (H-9) References:
- Bifidobacterium bifidum improves intestinal integrity in a rat model of necrotizing enterocolitis. | Khailova, L., et al. 2009. Am J Physiol Gastrointest Liver Physiol. 297: G940-9. PMID: 20501441
- High recovery FASP applied to the proteomic analysis of microdissected formalin fixed paraffin embedded cancer tissues retrieves known colon cancer markers. | Wiśniewski, JR., et al. 2011. J Proteome Res. 10: 3040-9. PMID: 21526778
- Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway. | Zhou, Y., et al. 2014. Mol Biol Cell. 25: 2882-90. PMID: 25057011
- Endoscopic papillectomy for carcinoma of the ampulla of Vater: possible standardization based on endoscopy and immunohistochemistry. | Yoshihiro, H., et al. 2014. Turk J Gastroenterol. 25: 563-7. PMID: 25417620
- Saturated and Unsaturated Fatty Acids Differently Modulate Colonic Goblet Cells In Vitro and in Rat Pups. | Benoit, B., et al. 2015. J Nutr. 145: 1754-62. PMID: 26108543
- Partial Enteral Nutrition Preserves Elements of Gut Barrier Function, Including Innate Immunity, Intestinal Alkaline Phosphatase (IAP) Level, and Intestinal Microbiota in Mice. | Wan, X., et al. 2015. Nutrients. 7: 6294-312. PMID: 26247961
- Farnesoid X receptor signal is involved in deoxycholic acid-induced intestinal metaplasia of normal human gastric epithelial cells. | Li, S., et al. 2015. Oncol Rep. 34: 2674-82. PMID: 26324224
- Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model. | Song, CH., et al. 2018. Gut Liver. 12: 682-693. PMID: 30400733
- Proinflammatory Polarization of Macrophages Causes Intestinal Inflammation in Low-Birth-Weight Piglets and Mice. | Zhang, X., et al. 2023. J Nutr. 153: 1803-1815. PMID: 37084872
- Morphological and functional features of the colonic mucus barrier in patients with symptomatic uncomplicated diverticular disease and acute uncomplicated diverticulitis. | Dorohavtseva, HA., et al. 2024. Wiad Lek. 77: 1331-1337. PMID: 39241130
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mucin 2/MUC2 Antibody (H-9) | sc-515106 | 200 µg/ml | $322.00 | |||
Mucin 2/MUC2 Antibody (H-9): m-IgGκ BP-HRP Bundle | sc-524936 | 200 µg Ab, 40 µg BP | $361.00 | |||
Mucin 2/MUC2 Antibody (H-9): m-IgG2b BP-HRP Bundle | sc-549199 | 200 µg Ab; 10 µg BP | $361.00 | |||
Mucin 2/MUC2 Antibody (H-9) AC | sc-515106 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Mucin 2/MUC2 Antibody (H-9) HRP | sc-515106 HRP | 200 µg/ml | $322.00 | |||
Mucin 2/MUC2 Antibody (H-9) FITC | sc-515106 FITC | 200 µg/ml | $336.00 | |||
Mucin 2/MUC2 Antibody (H-9) PE | sc-515106 PE | 200 µg/ml | $349.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 488 | sc-515106 AF488 | 200 µg/ml | $364.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 546 | sc-515106 AF546 | 200 µg/ml | $364.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 594 | sc-515106 AF594 | 200 µg/ml | $364.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 647 | sc-515106 AF647 | 200 µg/ml | $364.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 680 | sc-515106 AF680 | 200 µg/ml | $364.00 | |||
Mucin 2/MUC2 Antibody (H-9) Alexa Fluor® 790 | sc-515106 AF790 | 200 µg/ml | $364.00 |