아미노 산878-917 within an extracellular domain of Integrin α7 of human origin 간의 피토프 매핑 에 특이적인다
안티-Integrin α7/ITGA7 항체 (E-2)는 WB, IP, IF, IHC(P) and ELISA으로 mouse, rat and human유래의 precursor and mature heavy chain Integrin α7 를 감지하는 데에 추천한다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-Integrin α7/ITGA7 항체 (E-2)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Integrin α7/ITGA7 Antibody (E-2) for WB and IHC(P) applications. These reagents are now offered in bundles with Integrin α7/ITGA7 Antibody (E-2) (see ordering information below).
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Integrin α7 Antibody (E-2) is a high quality monoclonal Integrin alpha 7 antibody (also designated Integrin alpha-7 antibody or ITGA7 antibody) suitable for the detection of the Integrin alpha 7 protein of mouse, rat and human origin. Integrin α7 Antibody (E-2) is available as both the non-conjugated anti-Integrin alpha 7 antibody form, as well as multiple conjugated forms of anti-Integrin alpha 7 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences