CD7 Antibody (SBCV9.1): sc-53568

CD7 Antibody (SBCV9.1) is a mouse monoclonal IgG2b antibody that recognizes CD7 in human samples through western blotting (WB) and flow cytometry (FCM). CD7 is a type I transmembrane glycoprotein that plays a crucial role in the immune system, particularly in T cell activation and differentiation. CD7 monoclonal antibody (SBCV9.1) targets a protein predominantly expressed on pluripotential hematopoietic cells, most human thymocytes, and a subset of peripheral blood T cells, making CD7 (SBCV9.1) antibody a significant marker for various hematological malignancies, including pluripotential stem cell leukemias and T cell acute lymphocytic leukemia. CD7′s importance extends beyond its role as a marker; CD7 is involved in the activation of T cells with gamma/delta receptors, which are essential for immune responses against certain pathogens. Notably, CD7 expression is down-regulated in CD8 T cells from patients infected with HIV-1, highlighting CD7′s potential as a biomarker for disease progression and immune dysfunction. Additionally, CD7 is among the pan-T-cell antigens that are down-regulated during acute infectious mononucleosis, further emphasizing CD7′s relevance in T cell biology and immune response. With high specificity and reliability, anti-CD7 antibody (SBCV9.1) serves as an invaluable tool for researchers studying T cell dynamics and related pathologies.

The preferred CD7 antibody is CD7 Antibody (CBC.37): sc-59108.