CD7 Antibody (Huly-m2): sc-7631
- CD7 Antibody (Huly-m2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against human thymocytes
- recommended for detection of CD7 of human origin by IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD7 Antibody (Huly-m2). These reagents are now offered in bundles with CD7 Antibody (Huly-m2) (see ordering information below).
QUICK LINKS
SEE ALSO...
CD7 Antibody (Huly-m2) is a mouse monoclonal IgG2a antibody that detects CD7 in human samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM) applications. CD7 is a type I transmembrane glycoprotein predominantly expressed on pluripotent hematopoietic cells, most human thymocytes, and certain peripheral blood T cells, playing a crucial role in T cell activation and signaling. CD7 expression serves as a marker for various hematological malignancies, including pluripotent stem cell leukemias and T cell acute lymphoblastic leukemia. CD7 has been implicated in the activation of T cells with gamma/delta receptors, highlighting its importance in immune responses. Studies have shown that CD8 T cells from HIV-1-infected patients exhibit a marked down-regulation of CD7 expression compared to healthy individuals, indicating CD7′s potential role in immune evasion during viral infections. CD7 is one of the pan-T-cell antigens that are down-regulated during acute infectious mononucleosis, underscoring CD7′s relevance in both normal and pathological immune processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD7 Antibody (Huly-m2) | sc-7631 | 200 µg/ml | $322.00 | |||
CD7 Antibody (Huly-m2): m-IgG Fc BP-HRP Bundle | sc-536558 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD7 Antibody (Huly-m2): m-IgGκ BP-HRP Bundle | sc-533709 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD7 Antibody (Huly-m2) FITC | sc-7631 FITC | 200 µg/ml | $336.00 | |||
CD7 Antibody (Huly-m2) PE | sc-7631 PE | 200 µg/ml | $349.00 |