CD19 Antibody (PDR134): sc-53191
- CD19 Antibody (PDR134) is a mouse monoclonal IgM κ, cited in 1 publications, provided at 200 µg/ml
- raised against Pokeweek-stimulated Daudi and Raji cells of human origin
- recommended for detection of CD19 of human origin by WB, IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD19 (B-1): sc-390244 for CD19 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for CD19 Antibody (PDR134) for WB applications. This reagent is now offered in a bundle with CD19 Antibody (PDR134) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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CD19 Antibody (PDR134) is a mouse monoclonal IgM kappa light chain antibody that detects CD19 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD19 is a crucial transmembrane glycoprotein that plays a significant role in B-cell development and function, as CD19 is selectively expressed on the surface of B-lymphocytes. CD19 contains two extracellular immunoglobulin-like domains, which are essential for interaction with other proteins and for initiating intracellular signaling cascades. Notably, CD19 is involved in activating pathways such as Ras and phosphatidylinositol 3-kinase, which are vital for B-cell activation and proliferation. CD19′s importance extends to forming functional complexes with other B-lymphocyte surface proteins, including integrin β1, CD21, and CD81, which collectively regulate B-cell development and enhance the immune response. CD19′s expression is maintained throughout B-cell maturation and persists even during the terminal differentiation of B-cells into plasma cells, underscoring CD19′s critical role in the adaptive immune system.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD19 Antibody (PDR134) | sc-53191 | 200 µg/ml | $322.00 | |||
CD19 Antibody (PDR134): m-IgGκ BP-HRP Bundle | sc-552779 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD19 Antibody (PDR134) FITC | sc-53191 FITC | 200 µg/ml | $336.00 | |||
CD19 Antibody (PDR134) PE | sc-53191 PE | 200 µg/ml | $349.00 |