Date published: 2026-10-28

1-800-457-3801

SCBT Portrait Logo
Seach Input

Calgranulin B Antibody (F-4): sc-373704

5.0(3)
Write a reviewAsk a question
Datasheets
  • Calgranulin B Antibody (F-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 25-114 of Calgranulin B of human origin
  • recommended for detection of Calgranulin B of human origin by WB, IP, IF, IHC(P) and ELISA
  • See Calgranulin B (B-5): sc-376772 for Calgranulin B antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Calgranulin B Antibody (F-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Calgranulin B Antibody (F-4) (see ordering information below).
    Gene Editing Promo Banner

    QUICK LINKS

    SEE ALSO...

    Calgranulin B Antibody (F-4) is a mouse monoclonal IgG1 antibody that detects Calgranulin B in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Calgranulin B, also known as MRP14, is a member of the S100 protein family and plays a crucial role in inflammatory response and cellular signaling. Anti-Calgranulin B antibody (F-4) targets a protein primarily located in macrophages and epithelial cells, where Calgranulin B is involved in regulating calcium homeostasis and modulating immune responses. Calgranulin B in these cells contributes to recruiting and activating immune cells during inflammation, thereby influencing overall immune response. Calgranulin B monoclonal antibody (F-4) enables research into various pathological conditions, including cancer and autoimmune diseases, making Calgranulin B an important target for research and therapeutic interventions. With versatile applications and critical role in immune function, anti-Calgranulin B antibody (F-4) serves as an essential tool for researchers studying inflammation and immune-related processes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Calgranulin B Antibody (F-4) References:

    1. Ovarian cyst fluids are a cache of tumor biomarkers that include calgranulin A and calgranulin B isoforms.  |  Skaggs, HS., et al. 2013. Cancer Invest. 31: 433-53. PMID: 23915068
    2. Injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages.  |  Wang, J., et al. 2015. FASEB J. 29: 250-62. PMID: 25342131
    3. Antitumor effects of calgranulin B internalized in human colon cancer cells.  |  Kim, K., et al. 2016. Oncotarget. 7: 20368-80. PMID: 26933915
    4. Cellular Distribution and Gene Expression Pattern of Metastasin (S100A4), Calgranulin A (S100A8), and Calgranulin B (S100A9) in Oral Lesions as Markers for Molecular Pathology.  |  Reckenbeil, J., et al. 2016. Cancer Invest. 34: 246-54. PMID: 27294692
    5. Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116.  |  Myung, JK., et al. 2017. Oncotarget. 8: 6819-6832. PMID: 28036279
    6. Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells.  |  Kim, KH., et al. 2017. PLoS One. 12: e0171232. PMID: 28152021
    7. MRP14 is dispensable for LPS-induced shock in BALB/c mice.  |  Mizobuchi, H., et al. 2018. Immunol Lett. 194: 13-20. PMID: 29253495
    8. Calgranulin B and KL-6 in Bronchoalveolar Lavage of Patients with IPF and NSIP.  |  Bennett, D., et al. 2019. Inflammation. 42: 463-470. PMID: 30680696
    9. MRP14 enhances the ability of macrophage to recruit T cells and promotes obesity-induced insulin resistance.  |  Xia, C., et al. 2019. Int J Obes (Lond). 43: 2434-2447. PMID: 31040394
    10. Pathological roles of MRP14 in anemia and splenomegaly during experimental visceral leishmaniasis.  |  Ishizuka, K., et al. 2020. PLoS Negl Trop Dis. 14: e0008020. PMID: 31961866

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Calgranulin B Antibody (F-4)

    sc-373704
    200 µg/ml
    $322.00

    Calgranulin B Antibody (F-4): m-IgG Fc BP-HRP Bundle

    sc-540389
    200 µg Ab; 10 µg BP
    $361.00

    Calgranulin B Antibody (F-4): m-IgG1 BP-HRP Bundle

    sc-542090
    200 µg Ab; 20 µg BP
    $361.00

    Can Calgranulin B (F-4): sc-373704 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: jenniferc
    Thank you for your question. Yes, Calgranulin B (F-4): sc-373704 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-25
    • y_2026, m_10, d_27, h_5CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_en_US, sid_373704, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 76ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by SS from Strong band in WB in DMSO treated HLStrong band in WB in DMSO treated HL-60 whole cell lysate. -SCBT QC
    Date published: 2015-04-09
    Rated 5 out of 5 by SF from Positive signal in WB in human PBL wholePositive signal in WB in human PBL whole cell lysate. -SCBT QC
    Date published: 2015-03-05
    Rated 5 out of 5 by MS from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human esophagus tissue. -SCBT QC
    Date published: 2015-01-08
    • y_2026, m_10, d_27, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_en_US, sid_373704, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 9ms
    • REVIEWS, PRODUCT
    Calgranulin B Antibody (F-4) is rated 5.0 out of 5 by 3.
    • y_2026, m_10, d_27, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_en_US, sid_373704, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 85ms
    • REVIEWS, PRODUCT