Date published: 2026-8-19

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Smo Antibodies

Santa Cruz Biotechnology features a diverse variety of Smo Antibodies for advanced research in cell signaling and development. Smo Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smoothened (Smo) functions as a key component of the Hedgehog signaling pathway, regulating cell growth, differentiation, and tissue patterning during embryonic development. Smo expression patterns can be effectively analyzed using specific detection methods across various experimental applications. Understanding Smo activity provides valuable insights into cellular development and tissue organization. Abnormal Smo function has been linked to various cancers and developmental disorders, highlighting its significance in disease research. Investigating Smo mechanisms helps identify new therapeutic approaches for treating related pathologies. Santa Cruz Biotechnology monoclonal antibodies for Smo research enable scientists to make meaningful contributions to understanding disease mechanisms and developing targeted treatments.

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Smo Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SMO/Smoothened Antibody (E-5)

sc-166685mouse IgG2a κ488-787 (h)WB, IP, IF, ELISAm, r, h
95
(13)

Smo siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMO/Smoothened siRNA (h)

sc-40161hGene SilencingN/A
8
(0)

SMO/Smoothened shRNA Plasmid (h)

sc-40161-SHhGene SilencingPuromycin
8
(0)

SMO/Smoothened shRNA (h) Lentiviral Particles

sc-40161-VhGene SilencingPuromycin
8
(0)

SMO/Smoothened siRNA (m)

sc-40162mGene SilencingN/A0
(0)

SMO/Smoothened shRNA Plasmid (m)

sc-40162-SHmGene SilencingPuromycin0
(0)

SMO/Smoothened shRNA (m) Lentiviral Particles

sc-40162-VmGene SilencingPuromycin0
(0)

Smo CRISPR Knockout (KO) and HDR Plasmids

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SMO/Smoothened CRISPR/Cas9 KO Plasmid (h)

sc-400491Gene Knockouth0
(0)

SMO/Smoothened HDR Plasmid (h)

sc-400491-HDRHomology Directed Repairh0
(0)

SMO/Smoothened CRISPR/Cas9 KO Plasmid (m)

sc-435662Gene Knockoutm0
(0)

SMO/Smoothened HDR Plasmid (m)

sc-435662-HDRHomology Directed Repairm0
(0)

Smo CRISPR Double Nickase Plasmids

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SMO/Smoothened Double Nickase Plasmid (h)

sc-400491-NICGene Knockouth0
(0)

SMO/Smoothened Double Nickase Plasmid (h2)

sc-400491-NIC-2Gene Knockouth0
(0)

SMO/Smoothened Double Nickase Plasmid (m)

sc-435662-NICGene Knockoutm0
(0)

SMO/Smoothened Double Nickase Plasmid (m2)

sc-435662-NIC-2Gene Knockoutm0
(0)

Smo CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SMO/Smoothened CRISPR Activation Plasmid (h)

sc-400491-ACTGene Activationh0
(0)