Date published: 2026-7-15

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IL-6R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IL-6R monoclonal antibodies for various research applications. IL-6R Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Interleukin-6 receptor (IL-6R) plays a crucial role in the immune response, inflammation, and hematopoiesis. IL-6R is involved in the signaling pathways that mediate the effects of interleukin-6, a cytokine that influences the differentiation of immune cells and the acute phase response. Dysregulation of IL-6R signaling has been implicated in various diseases, including autoimmune disorders and cancers, making it a significant target for therapeutic intervention. Researchers worldwide utilize IL-6R monoclonal antibodies to explore cellular mechanisms and pathways related to immune system function. Understanding IL-6R's molecular interactions and signaling cascades can lead to improved therapeutic strategies for inflammatory conditions. IL-6R monoclonal antibodies enable detailed investigation of receptor expression patterns across different cell types and tissues. Santa Cruz Biotechnology monoclonal antibodies support researchers in advancing scientific knowledge and developing potential therapeutic approaches for IL-6R-related diseases.

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IL-6R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-6Rα Antibody (D-8)

sc-374259mouse IgG1 κ433-460 (m)WB, IP, IF, ELISAm, r
14
(5)

IL-6Rα Antibody (H-7)

sc-373708mouse IgG1 κ441-468 (h)WB, IP, IF, IHC(P), ELISAm, r, h
28
(8)

IL-6Rα Antibody (2B2.3)

sc-71366mouse IgG1(h)FCM
1
(1)

IL-6R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IL-6Rα siRNA (h)

sc-35663hGene SilencingN/A
5
(0)

IL-6Rα shRNA Plasmid (h)

sc-35663-SHhGene SilencingPuromycin
5
(0)

IL-6Rα shRNA (h) Lentiviral Particles

sc-35663-VhGene SilencingPuromycin
5
(0)

IL-6Rα siRNA (m)

sc-40065mGene SilencingN/A
2
(0)

IL-6Rα shRNA Plasmid (m)

sc-40065-SHmGene SilencingPuromycin
2
(0)

IL-6Rα shRNA (m) Lentiviral Particles

sc-40065-VmGene SilencingPuromycin
2
(0)

IL-6R CRISPR Knockout (KO) and HDR Plasmids

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IL-6Rα CRISPR/Cas9 KO Plasmid (h2)

sc-400582-KO-2Gene Knockouth0
(0)

IL-6Rα HDR Plasmid (h2)

sc-400582-HDR-2Homology Directed Repairh0
(0)

IL-6Rα CRISPR/Cas9 KO Plasmid (m)

sc-421115Gene Knockoutm0
(0)

IL-6Rα HDR Plasmid (m)

sc-421115-HDRHomology Directed Repairm0
(0)

IL-6R CRISPR Double Nickase Plasmids

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IL-6Rα Double Nickase Plasmid (h)

sc-400582-NICGene Knockouth0
(0)

IL-6Rα Double Nickase Plasmid (h2)

sc-400582-NIC-2Gene Knockouth0
(0)

IL-6R CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

IL-6Rα CRISPR Activation Plasmid (h)

sc-400582-ACTGene Activationh0
(0)

IL-6Rα CRISPR Activation Plasmid (h2)

sc-400582-ACT-2Gene Activationh0
(0)