Date published: 2026-6-3

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EAAT Antibodies

Santa Cruz Biotechnology features a diverse variety of EAAT Antibodies for investigating excitatory amino acid transporters. EAAT Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Excitatory amino acid transporters play a critical role in regulating synaptic transmission and maintaining glutamate homeostasis in the central nervous system. By controlling extracellular levels of glutamate, EAATs are essential for preventing excitotoxicity, which can lead to neurodegenerative diseases. Understanding the function and regulation of EAATs is crucial for developing therapeutic strategies for conditions such as epilepsy, Alzheimer's disease, and other neurological disorders. EAAT research continues to reveal new insights into neurotransmitter regulation and cellular communication pathways. Investigating EAAT expression patterns helps identify potential therapeutic targets in neurological conditions. Advanced research techniques using monoclonal antibodies enable detailed analysis of EAAT localization and function. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing neuroscience and contributing to the development of new therapeutic approaches for neurological disorders.

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EAAT Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

EAAT1 Antibody (A-3)

sc-515839mouse IgG2a κ1-50 (h)WB, IP, IF, ELISAm, r, h
21
(5)

EAAT2 Antibody (E-1)

sc-365634mouse IgG2b κ1-85 (h)WB, IP, IF, ELISAm, r, h
47
(21)

EAAT2 Antibody (20)

sc-135892mouse IgG1562-574 (h)WB, IPm, r, h
1
(1)

EAAT4 Antibody (6D9)

sc-293344mouse IgG1 κ500-564 (h)WB, IP, ELISAm, r, h
1
(1)

EAAT CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

EAAT1 CRISPR/Cas9 KO Plasmid (h)

sc-400917hGene KnockoutGFP0
(0)

EAAT1 CRISPR/Cas9 KO Plasmid (m)

sc-422985mGene KnockoutGFP0
(0)

EAAT1 HDR Plasmid (m)

sc-422985-HDRmHomology Directed RepairPuromycin0
(0)

EAAT2 CRISPR/Cas9 KO Plasmid (m)

sc-422984mGene KnockoutGFP0
(0)

EAAT4 CRISPR/Cas9 KO Plasmid (m)

sc-422986mGene KnockoutGFP0
(0)

EAAT CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

EAAT1 CRISPR Activation Plasmid (h)

sc-400917-ACThGene ActivationPuro, Blast, Hygro0
(0)

EAAT3 CRISPR Activation Plasmid (h)

sc-401539-ACThGene ActivationPuro, Blast, Hygro0
(0)

EAAT siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

EAAT1 siRNA (h)

sc-35253hGene SilencingN/A
1
(0)

EAAT1 shRNA Plasmid (h)

sc-35253-SHhGene SilencingPuromycin
1
(0)

EAAT1 shRNA (h) Lentiviral Particles

sc-35253-VhGene SilencingPuromycin
1
(0)

EAAT1 siRNA (m)

sc-35254mGene SilencingN/A0
(0)

EAAT1 shRNA Plasmid (m)

sc-35254-SHmGene SilencingPuromycin0
(0)

EAAT1 shRNA (m) Lentiviral Particles

sc-35254-VmGene SilencingPuromycin0
(0)

EAAT1 siRNA (r)

sc-270105rGene SilencingN/A0
(0)

EAAT1 shRNA Plasmid (r)

sc-270105-SHrGene SilencingPuromycin0
(0)

EAAT1 shRNA (r) Lentiviral Particles

sc-270105-VrGene SilencingPuromycin0
(0)

EAAT2 siRNA (h)

sc-35255hGene SilencingN/A
1
(0)

EAAT2 shRNA Plasmid (h)

sc-35255-SHhGene SilencingPuromycin
1
(0)

EAAT2 shRNA (h) Lentiviral Particles

sc-35255-VhGene SilencingPuromycin
1
(0)

EAAT2 siRNA (m)

sc-35256mGene SilencingN/A
1
(0)

EAAT2 shRNA Plasmid (m)

sc-35256-SHmGene SilencingPuromycin
1
(0)

EAAT2 shRNA (m) Lentiviral Particles

sc-35256-VmGene SilencingPuromycin
1
(0)

EAAT2 siRNA (r)

sc-270106rGene SilencingN/A0
(0)

EAAT2 shRNA Plasmid (r)

sc-270106-SHrGene SilencingPuromycin0
(0)

EAAT2 shRNA (r) Lentiviral Particles

sc-270106-VrGene SilencingPuromycin0
(0)

EAAT3 siRNA (h)

sc-41940hGene SilencingN/A0
(0)

EAAT3 shRNA Plasmid (h)

sc-41940-SHhGene SilencingPuromycin0
(0)

EAAT3 shRNA (h) Lentiviral Particles

sc-41940-VhGene SilencingPuromycin0
(0)

EAAT3 siRNA (m)

sc-41941mGene SilencingN/A0
(0)

EAAT3 shRNA Plasmid (m)

sc-41941-SHmGene SilencingPuromycin0
(0)

EAAT3 shRNA (m) Lentiviral Particles

sc-41941-VmGene SilencingPuromycin0
(0)

EAAT4 siRNA (h)

sc-41942hGene SilencingN/A0
(0)

EAAT4 shRNA Plasmid (h)

sc-41942-SHhGene SilencingPuromycin0
(0)

EAAT4 shRNA (h) Lentiviral Particles

sc-41942-VhGene SilencingPuromycin0
(0)

EAAT4 siRNA (m)

sc-41943mGene SilencingN/A0
(0)

EAAT4 shRNA Plasmid (m)

sc-41943-SHmGene SilencingPuromycin0
(0)

EAAT4 shRNA (m) Lentiviral Particles

sc-41943-VmGene SilencingPuromycin0
(0)

EAAT5 siRNA (h)

sc-41944hGene SilencingN/A0
(0)

EAAT5 shRNA Plasmid (h)

sc-41944-SHhGene SilencingPuromycin0
(0)

EAAT5 shRNA (h) Lentiviral Particles

sc-41944-VhGene SilencingPuromycin0
(0)

EAAT5 siRNA (m)

sc-41945mGene SilencingN/A0
(0)

EAAT5 shRNA Plasmid (m)

sc-41945-SHmGene SilencingPuromycin0
(0)

EAAT5 shRNA (m) Lentiviral Particles

sc-41945-VmGene SilencingPuromycin0
(0)