Troponin I-SS Antibody (C-4): sc-514899
- Troponin I-SS Antibody (C-4) is a mouse monoclonal IgG1 κ Troponin I-SS antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 166-187 at the C-terminus of Troponin I-SS of human origin
- Troponin I-SS Antibody (C-4) is recommended for detection of Troponin I-SS of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Troponin I-SS Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Troponin I-SS Antibody (C-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Troponin I-SS Antibody (C-4) (see ordering information below).
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Troponin I-SS Antibody (C-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Troponin I-SS protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Troponin I-SS antibody (C-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Troponin I-SS protein plays a critical role in muscle contraction by regulating the interaction between actin and myosin, which are essential for muscle fiber contraction and relaxation. This regulation is particularly important in cardiac and skeletal muscle, where precise control of contraction is vital for proper heart function and movement. Troponin I-SS is part of the troponin complex, which also includes Troponin C and Troponin T, and calcium ion binding capability is crucial for initiating muscle contraction. Different isoforms of Troponin I in various muscle types allow for specialized functions, making Troponin I-SS a key player in muscle physiology. Anti-Troponin I-SS antibody (C-4) enables researchers to gain insights into muscle function and underlying mechanisms of muscle-related diseases, enhancing understanding of both normal physiology and pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Troponin I-SS Antibody (C-4) References:
- Structure and expression of the murine slow/cardiac troponin C gene. | Parmacek, MS. and Leiden, JM. 1989. J Biol Chem. 264: 13217-25. PMID: 2753913
- cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs. | Koppe, RI., et al. 1989. J Biol Chem. 264: 14327-33. PMID: 2760067
- A direct regulatory role for troponin T and a dual role for troponin C in the Ca2+ regulation of muscle contraction. | Potter, JD., et al. 1995. J Biol Chem. 270: 2557-62. PMID: 7852318
- Structure and regulation of the mouse cardiac troponin I gene. | Ausoni, S., et al. 1994. J Biol Chem. 269: 339-46. PMID: 8276817
- Actin cytoskeleton. Setting the pace of cell movement. | Barkalow, K. and Hartwig, JH. 1995. Curr Biol. 5: 1000-2. PMID: 8542272
- Myosins: matching functions with motors. | Baker, JP. and Titus, MA. 1998. Curr Opin Cell Biol. 10: 80-6. PMID: 9484598
- A new look at thin filament regulation in vertebrate skeletal muscle. | Squire, JM. and Morris, EP. 1998. FASEB J. 12: 761-71. PMID: 9657517
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin I-SS Antibody (C-4) | sc-514899 | 200 µg/ml | $322.00 | |||
Troponin I-SS Antibody (C-4): m-IgG Fc BP-HRP Bundle | sc-527956 | 200 µg Ab; 10 µg BP | $361.00 | |||
Troponin I-SS Antibody (C-4): m-IgG1 BP-HRP Bundle | sc-533329 | 200 µg Ab; 20 µg BP | $361.00 | |||
Troponin I-SS Antibody (C-4) AC | sc-514899 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Troponin I-SS Antibody (C-4) HRP | sc-514899 HRP | 200 µg/ml | $322.00 | |||
Troponin I-SS Antibody (C-4) FITC | sc-514899 FITC | 200 µg/ml | $336.00 | |||
Troponin I-SS Antibody (C-4) PE | sc-514899 PE | 200 µg/ml | $349.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 488 | sc-514899 AF488 | 200 µg/ml | $364.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 546 | sc-514899 AF546 | 200 µg/ml | $364.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 594 | sc-514899 AF594 | 200 µg/ml | $364.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 647 | sc-514899 AF647 | 200 µg/ml | $364.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 680 | sc-514899 AF680 | 200 µg/ml | $364.00 | |||
Troponin I-SS Antibody (C-4) Alexa Fluor® 790 | sc-514899 AF790 | 200 µg/ml | $364.00 | |||
Troponin I-SS (C-4) Neutralizing Peptide | sc-514899 P | 100 µg/0.5 ml | $69.00 |