Septin 5 Antibody (H-7): sc-390729
- Septin 5 Antibody (H-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 301-332 of Septin 5 of human origin
- recommended for detection of Septin 5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Septin 5 Antibody (H-7) for WB applications. These reagents are now offered in bundles with Septin 5 Antibody (H-7) (see ordering information below).
Septin 5 Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects Septin 5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Septin 5 plays a crucial role in the organization of the cytoskeleton and is involved in various cellular processes, including cytokinesis and the regulation of exocytosis. Septin 5 localizes primarily in the cytoplasm and at the cell membrane, where anti-Septin 5 antibody (H-7) can detect its contribution to the formation of septin filaments essential for maintaining cellular integrity and facilitating cell division. Septin 5′s ability to form heteropolymeric complexes with other septins allows for the dynamic reorganization of the cytoskeleton, which is vital for processes such as cell migration and morphogenesis. Septin 5′s interaction with other proteins, including those involved in vesicle trafficking and membrane dynamics, underscores its importance in cellular signaling pathways. Septin 5 (H-7) antibody serves as an invaluable tool for researchers studying the intricate roles of septins in cellular function and their implications in various diseases, including neurodegenerative disorders.
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Septin 5 Antibody (H-7) References:
- Cerebellar protein expression in three different mouse strains and their relevance for motor performance. | Pollak, D., et al. 2005. Neurochem Int. 46: 19-29. PMID: 15567512
- Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. | Suzuki, G., et al. 2009. Hum Mol Genet. 18: 1652-60. PMID: 19240081
- Proteomic analysis of proteins expressing in regions of rat brain by a combination of SDS-PAGE with nano-liquid chromatography-quadrupole-time of flight tandem mass spectrometry. | Katagiri, T., et al. 2010. Proteome Sci. 8: 41. PMID: 20659346
- Synaptic protein deficits are associated with dementia irrespective of extreme old age. | Beeri, MS., et al. 2012. Neurobiol Aging. 33: 1125.e1-8. PMID: 22206847
- Cellular transcripts of chicken brain tissues in response to H5N1 and Newcastle disease virus infection. | Balasubramaniam, VR., et al. 2012. Virol J. 9: 53. PMID: 22361110
- A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. | Li, G., et al. 2012. Toxicol Sci. 127: 485-95. PMID: 22430071
- Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat. | Ganesan, MK., et al. 2014. Amino Acids. 46: 1681-96. PMID: 24682445
- Targeted multiplexed selected reaction monitoring analysis evaluates protein expression changes of molecular risk factors for major psychiatric disorders. | Wesseling, H., et al. 2014. Int J Neuropsychopharmacol. 18: PMID: 25539505
- Coexistence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4 Antibodies in Adult and Pediatric Patients. | Kunchok, A., et al. 2020. JAMA Neurol. 77: 257-259. PMID: 31657826
- Diagnostic value of aquaporin-4-IgG live cell based assay in neuromyelitis optica spectrum disorders. | Redenbaugh, V., et al. 2021. Mult Scler J Exp Transl Clin. 7: 20552173211052656. PMID: 34868626
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Septin 5 Antibody (H-7) | sc-390729 | 200 µg/ml | $322.00 | |||
Septin 5 Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-540844 | 200 µg Ab; 10 µg BP | $361.00 | |||
Septin 5 Antibody (H-7): m-IgG1 BP-HRP Bundle | sc-542411 | 200 µg Ab; 20 µg BP | $361.00 | |||
Septin 5 (H-7) Neutralizing Peptide | sc-390729 P | 100 µg/0.5 ml | $69.00 |