Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The Reticulon (Rtn) family consists of four members: Rtn-1 (also designated neuroendocrine-specific protein or NSP), Rtn-2 (also designated NSP-like-1), Rtn-3 (also designated NSP-like-2) and Nogo (also designated Rtn-4A). Reticulon proteins are anchored to the membranes of the endoplasmic reticulum through their common C-terminal regions. Localized on human chromosome 14q23.1, the gene encoding Rtn-1 is expressed as three isoforms: Rtn-1A (NSP-A), Rtn-1B (NSP-B) and Rtn-1C (NSP-C), which are produced by alternative splicing, are anchored to the endoplasmic reticulum in neural and neuroendocrine tissues and cells, and may be involved in neuroendocrine secretion or in membrane trafficking. In lung cancer diagnosis, Rtn-1A appears to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors show expression of Rtn-1A. Rtn-1B exists as multiple forms. Expression of Rtn-1C strongly correlates with neuronal differentiation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.