Laminin β-1 Antibody (A-1): sc-17810

Laminin β-1 Antibody (A-1) is a mouse monoclonal IgG3 kappa light chain antibody that detects Laminin beta-1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Laminin beta-1 antibody (A-1) is available as a non-conjugated format. Laminins play a crucial role in forming and maintaining basement membranes, which are specialized extracellular matrices that provide structural support to tissues and influence various cellular processes. Laminin beta-1 is a key component of these matrices, consisting of a heterotrimeric structure formed by α, β, and γ chain subunits. This unique structure allows laminins to self-assemble and interact with other matrix components, such as type IV collagen and proteoglycans, facilitating stable basement membrane formation. These membranes are essential for maintaining tissue integrity and regulating cell behavior, including proliferation, migration, and differentiation. The human Laminin β-1 gene is located on chromosome 7q22 and is widely expressed in tissues that produce basement membranes, highlighting its importance in both normal physiology and potential pathological conditions. Anti-Laminin beta-1 antibody (A-1) serves as an invaluable tool for researchers studying basement membrane formation dynamics and implications in various diseases, including cancer and fibrosis.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Laminin β-1 Antibody (A-1) has 13 citations in a variety of scientific publications.

Primary antibodies like Anti-Laminin β-1 Antibody (A-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Laminin β-1 Antibody (A-1) Specifications

Alternate Product Name: Laminin β-1

Product Clone Name: A-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 1487-1786

Epitope Target: Laminin β-1

Epitope Species: human

Product Reactivity/Detection: Laminin β-1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 13 citations in various scientific publications

Available Conjugates/Forms for Laminin β-1 Antibody (A-1): N/A

The preferred Laminin β-1 antibody is Laminin β-1 Antibody (LT3): sc-33709.