Filamin 1 Antibody (G-9): sc-271440
- Filamin 1 Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 2348-2647 mapping at the C-terminus of Filamin 1 of human origin
- recommended for detection of Filamin 1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Filamin 1 (E-3): sc-17749 for Filamin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Filamin 1 Antibody (G-9) for WB applications. These reagents are now offered in bundles with Filamin 1 Antibody (G-9) (see ordering information below).
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Filamin 1 Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects Filamin 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Filamin 1 is a crucial actin-binding protein that plays a significant role in maintaining the structural integrity of the cytoskeleton by crosslinking actin filaments into a three-dimensional network, which is essential for various cellular processes, including cell shape, motility, and signaling. Filamin 1 exists as a homodimer and is ubiquitously expressed, allowing participation in diverse cellular functions across different tissue types. Filamin 1′s ability to organize actin filaments is vital for processes such as cell migration and mechanotransduction, where cells respond to mechanical stimuli. Additionally, Filamin 1 interacts with numerous signaling molecules and other cytoskeletal proteins, which underscores its importance in cellular architecture and function. Filamin 1 (G-9) antibody is an invaluable tool for researchers studying cytoskeletal dynamics and related cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Filamin 1 Antibody (G-9) References:
- Filamin A phosphorylation by Akt promotes cell migration in response to arsenic. | Li, L., et al. 2015. Oncotarget. 6: 12009-19. PMID: 25944616
- Filamin A is required in injured axons for HDAC5 activity and axon regeneration. | Cho, Y., et al. 2015. J Biol Chem. 290: 22759-70. PMID: 26157139
- A review of filamin A mutations and associated interstitial lung disease. | Sasaki, E., et al. 2019. Eur J Pediatr. 178: 121-129. PMID: 30547349
- Expression levels of filamin A in preeclampsia placenta. | Zheng, LL., et al. 2020. J Biol Regul Homeost Agents. 34: 599-604. PMID: 32450679
- The androgen receptor/filamin A complex as a target in prostate cancer microenvironment. | Di Donato, M., et al. 2021. Cell Death Dis. 12: 127. PMID: 33500395
- Filamin A and parafibromin expression in parathyroid carcinoma. | Storvall, S., et al. 2021. Eur J Endocrinol. 185: 803-812. PMID: 34606470
- Targeting Filamin A alleviates ovariectomy-induced bone loss in mice via the WNT/β-catenin signaling pathway. | Yang, C., et al. 2022. Cell Signal. 90: 110191. PMID: 34774991
- Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner. | De Silva, E., et al. 2022. Biochem J. 479: 2351-2364. PMID: 36239738
- Filamin A is overexpressed in non-alcoholic steatohepatitis and contributes to the progression of inflammation and fibrosis. | Lu, Y., et al. 2023. Biochem Biophys Res Commun. 653: 93-101. PMID: 36863213
- Filamin A heart valve disease as a genetic cause of inherited bicuspid and tricuspid aortic valve disease. | Delwarde, C., et al. 2024. Heart. 110: 666-674. PMID: 38148157
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Filamin 1 Antibody (G-9) | sc-271440 | 200 µg/ml | $322.00 | |||
Filamin 1 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-540239 | 200 µg Ab; 10 µg BP | $361.00 | |||
Filamin 1 Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-541992 | 200 µg Ab; 20 µg BP | $361.00 |