CMV pp72 Antibody (CH443): sc-69747
- CMV pp72 Antibody (CH443) is a mouse monoclonal IgG2a, cited in 2 publications, provided at 100 µg/ml
- raised against CMV
- recommended for detection of pp72 of CMV origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CMV pp72 Antibody (CH443). This work is in progress.
CMV pp72 Antibody (CH443) is a mouse monoclonal IgG2a antibody that detects CMV pp72 in Cytomegalovirus (CMV) by western blotting (WB) and immunofluorescence (IF). CMV pp72 plays a crucial role during active CMV infection, as CMV pp72 interacts with another immediate early protein, CMV pp86, to enhance the expression of HLA-G, a non-classical major histocompatibility complex (MHC) class I molecule. This interaction is significant because HLA-G is involved in immune evasion, allowing the virus to persist in the host by inhibiting the activation of natural killer cells and cytotoxic T lymphocytes. The presence of CMV pp72 is indicative of viral replication and can serve as a marker for diagnosing CMV infections, particularly in immunocompromised patients who are at higher risk for severe disease. Anti-CMV pp72 antibody (CH443) is essential for researchers studying the mechanisms of CMV pathogenesis and the immune response to viral infections, providing valuable insights into potential therapeutic targets and vaccine development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CMV pp72 Antibody (CH443) | sc-69747 | 100 µg/ml | $322.00 |