C1r Antibody (F-1): sc-271642

C1r Antibody (F-1) is a mouse monoclonal IgG1 antibody that detects C1r in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). C1r is a crucial component of the complement system, specifically functioning as a serine protease that plays a vital role in the activation of the classical complement pathway. This pathway is essential for the immune response, as C1r helps to opsonize pathogens, promote inflammation, and facilitate the clearance of immune complexes. C1r exists as a dimer, which is activated through cleavage into two chains, A and B, allowing C1r to interact with C1q and C1s to form the C1 complex. This complex is pivotal for initiating the complement cascade, leading to the generation of anaphylatoxins that enhance the inflammatory response. Understanding the structure and function of C1r is important, as dysregulation of the complement system can lead to various autoimmune diseases and inflammatory conditions. Anti-C1r antibody (F-1) provides a reliable tool for researchers studying the complement system and its implications in health and disease.

The preferred C1r antibody is C1r Antibody (F-7): sc-514105.