SLMO2 アクチベーター

The PRELI domain is known to be involved in mitochondrial lipid transport and is a feature of proteins that participate in the regulation of mitochondrial morphology and function. Proteins with PRELI domains typically localize within the intermembrane space of mitochondria and can interact with other mitochondrial proteins to influence processes such as apoptosis, mitochondrial division, and the maintenance of mitochondrial DNA.

Given the shared domain, "PRELI domain containing 3B" likely plays a role in mitochondrial homeostasis, which is critical for cellular energy production, signaling, and apoptosis. Mitochondria are known as the powerhouses of the cell, generating most of the cell's supply of adenosine triphosphate (ATP), which is used as a source of chemical energy.Mitochondrial dysfunction is linked to a variety of diseases, including metabolic disorders, neurodegenerative diseases, and cancer. Proteins containing PRELI domains may therefore be important for maintaining mitochondrial integrity and function, and disruptions in their activity could contribute to disease pathogenesis.