Varicella Zoster Virus IE62 Antibody (0361): sc-58211

Varicella Zoster Virus IE62 Antibody (0361) is a mouse monoclonal IgG1 antibody that detects Varicella Zoster Virus IE62 protein through immunofluorescence (IF) in non-species reactive samples. Anti-Varicella Zoster Virus IE62 antibody (0361) is available as a non-conjugated format. Varicella Zoster Virus (VZV) causes two significant diseases: childhood chickenpox (varicella) and shingles (zoster). Understanding Varicella Zoster Virus IE62 protein structure is crucial, as Varicella Zoster Virus IE62 (0361) plays a vital role in establishing latency and reactivating later in life. Varicella Zoster Virus IE62 protein functions as a transcriptional regulatory protein essential for expressing other viral genes, facilitating viral replication and persistence within hosts. Varicella Zoster Virus IE62 protein′s ability to modulate host immune response helps VZV evade detection and destruction by immune systems. Varicella Zoster Virus IE62 protein interaction with host cell factors underscores significance in viral life cycles, making Varicella Zoster Virus IE62 (0361) antibody an invaluable tool for studying VZV infection dynamics and pathogenesis mechanisms.

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Varicella Zoster Virus IE62 Antibody (0361) References:

1. Transcription factor Sp1 is involved in the regulation of varicella-zoster virus glycoprotein E.  |  Rahaus, M. and Wolff, MH. 2000. Virus Res. 69: 69-81. PMID: 10989187
2. Essential role played by the C-terminal domain of glycoprotein I in envelopment of varicella-zoster virus in the trans-Golgi network: interactions of glycoproteins with tegument.  |  Wang, ZH., et al. 2001. J Virol. 75: 323-40. PMID: 11119602
3. Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates.  |  Kleinschmidt-DeMasters, BK. and Gilden, DH. 2001. Arch Pathol Lab Med. 125: 770-80. PMID: 11371229
4. Varicella-zoster virus glycoproteins E and I expressed in insect cells form a heterodimer that requires the N-terminal domain of glycoprotein I.  |  Kimura, H., et al. 1997. Virology. 233: 382-91. PMID: 9217061
5. Varicella-zoster virus glycoprotein I is essential for growth of virus in Vero cells.  |  Cohen, JI. and Nguyen, H. 1997. J Virol. 71: 6913-20. PMID: 9261418
6. Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking.  |  Mallory, S., et al. 1997. J Virol. 71: 8279-88. PMID: 9343180

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Varicella Zoster Virus IE62 Antibody (0361) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Varicella Zoster Virus IE62 Antibody (0361) Specifications

Alternate Product Name: Varicella Zoster Virus IE62

Product Clone Name: 0361

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Varicella Zoster Virus IE62

Epitope Species: Varicella Zoster virus

Product Reactivity/Detection: Varicella Zoster Virus Immediate Early protein encoded by Varicella Zoster Virus gene 62 (IE62)

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 50 µg IgG₁ in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for Varicella Zoster Virus IE62 Antibody (0361): N/A