Trx Antibody (1H6H6): sc-81155
- Trx Antibody (1H6H6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant Trx of human origin
- recommended for detection of Trx of human origin by WB and IP
- See Trx (A-5): sc-166393 for Trx antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Trx Antibody (1H6H6) for WB applications. These reagents are now offered in bundles with Trx Antibody (1H6H6) (see ordering information below).
Trx Antibody (1H6H6) is a mouse monoclonal IgG1 antibody that detects thioredoxin (Trx) in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-Trx antibody (1H6H6) recognizes thioredoxin, a crucial redox protein that plays a significant role in cellular processes by maintaining the redox balance within the cell. Located primarily in the cytoplasm, Trx is essential for protecting cells from oxidative stress, which can lead to cellular damage and contribute to various diseases, including cancer. Trx′s ability to act as a hydrogen donor for ribonucleotide reductase is vital for DNA synthesis, highlighting Trx′s importance in cell proliferation and survival. Additionally, Trx modulates the activity of several transcription factors, such as NFkB and p53, which are key regulators of cell growth and apoptosis. Trx′s interaction with these factors underscores Trx′s role in cellular signaling pathways and potential as a therapeutic target in cancer treatment, where Trx inhibitors have shown promising antitumor activity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trx Antibody (1H6H6) | sc-81155 | 200 µg/ml | $322.00 | |||
Trx Antibody (1H6H6): m-IgG Fc BP-HRP Bundle | sc-539592 | 200 µg Ab; 10 µg BP | $361.00 | |||
Trx Antibody (1H6H6): m-IgG1 BP-HRP Bundle | sc-541582 | 200 µg Ab; 20 µg BP | $361.00 |