Anti-TLR1 Antibody H-8 è un monoclonale di topo IgG1 (kappa light chain) TLR1 antibody fornito in 200 µg/ml
generato contro aminoacidi 161-250 mapping all´interno di un dominio extracellulare N-terminal dell´ TLR1 di origine human
TLR1 Antibody (H-8) é raccomandato per il rilevamento di TLR1 di origine mouse, rat e human in WB, IP, IF e ELISA
TLR1 Antibody (H-8) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di TLR1 (H-8): sc-514399.
m-IgG1 BP-HRP (mouse IgG1 binding protein-HRP) is the preferred secondary detection reagent for TLR1 Antibody (H-8) for WB applications. This reagent is now offered in a bundle with TLR1 Antibody (H-8) (see ordering information below).
TLR Attivatori per le analisi funzionali delle risposte cellulari a TLR
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TLR1 Antibody (H-8) is a high quality monoclonal TLR1 antibody (also designated Toll like receptor 1 antibody) suitable for the detection of the TLR1 protein of mouse, rat and human origin. TLR1 Antibody (H-8) is available as both the non-conjugated anti-TLR1 antibody form, as well as multiple conjugated forms of anti-TLR1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated Toll-like receptors (TLR). Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo and also participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFκB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages and monocytes. TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity, and, like other members of TLR family, it induces NFκB signaling upon activation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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