SLU7 Antibody (G-12): sc-393743
- SLU7 Antibody (G-12) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-22 at the N-terminus of SLU7 of human origin
- recommended for detection of SLU7 of human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-393743 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SLU7 Antibody (G-12) for WB applications. These reagents are now offered in bundles with SLU7 Antibody (G-12) (see ordering information below).
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SLU7 Antibody (G-12) is a mouse monoclonal IgG2a antibody that detects SLU7 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SLU7 plays a crucial role in the mRNA splicing process, specifically during the second catalytic step where SLU7 is essential for the accurate selection of the adenine-guanine (AG) dinucleotide at the 3′ splice site. This selection is vital for ensuring that the correct exons are joined together, which ultimately influences the production of properly spliced messenger RNA. The importance of SLU7 in maintaining the fidelity of splicing cannot be overstated, as errors in this process can lead to the generation of dysfunctional proteins and contribute to various diseases. SLU7 associates with the spliceosome late in the splicing pathway, and SLU7 depletion in HeLa nuclear extracts has demonstrated that SLU7 is necessary for holding exon 1 tightly within the spliceosome, facilitating the precise attack on the designated AG. With this significant role in mRNA processing, anti-SLU7 antibody (G-12) serves as an invaluable tool for researchers studying gene expression and splicing mechanisms in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SLU7 Antibody (G-12) | sc-393743 | 200 µg/ml | $322.00 | |||
SLU7 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-538298 | 200 µg Ab; 10 µg BP | $361.00 | |||
SLU7 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-535880 | 200 µg Ab; 40 µg BP | $361.00 | |||
SLU7 Antibody (G-12): m-IgG2a BP-HRP Bundle | sc-548261 | 200 µg Ab; 10 µg BP | $361.00 | |||
SLU7 (G-12) Neutralizing Peptide | sc-393743 P | 100 µg/0.5 ml | $69.00 | |||
SLU7 Antibody (G-12) X | sc-393743 X | 200 µg/0.1 ml | $322.00 |