NASP Antibody (A-6): sc-398379
- NASP Antibody (A-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 489-788 mapping at the C-terminus of NASP of human origin
- recommended for detection of NASP of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NASP Antibody (A-6) for WB applications. These reagents are now offered in bundles with NASP Antibody (A-6) (see ordering information below).
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NASP Antibody (A-6) is a mouse monoclonal IgG1 antibody that detects NASP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-NASP antibody (A-6) recognizes nuclear autoantigenic sperm protein, a crucial 788 amino acid protein involved in the transport of histones to the nucleus, thereby facilitating proper nucleosome assembly and ensuring effective DNA replication. NASP (A-6) antibody detects multiple alternatively-spliced isoforms, including a testis- and sperm-specific variant (tNASP) and a somatic cell variant (sNASP), highlighting diverse roles in different cell types. Nuclear autoantigenic sperm protein′s localization in both the nucleus and cytoplasm is vital for function, acting as a histone H1 binding protein that mediates histone transport, essential for normal cell cycle progression and cellular proliferation. NASP monoclonal antibody (A-6) recognizes a protein indispensable for spermatogenesis and normal development. In response to DNA damage, nuclear autoantigenic sperm protein undergoes phosphorylation by ATM or ATR, which may influence function and interactions within the cell.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NASP Antibody (A-6) | sc-398379 | 200 µg/ml | $322.00 | |||
NASP Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-538430 | 200 µg Ab; 10 µg BP | $361.00 | |||
NASP Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-536043 | 200 µg Ab; 40 µg BP | $361.00 | |||
NASP Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-545699 | 200 µg Ab; 20 µg BP | $361.00 |