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Melanoma Marker Antibody (NKI/C3): sc-52351

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Datasheets
  • Melanoma Marker Antibody (NKI/C3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against isolated melanoma cells of human origin
  • recommended for detection of Melanoma Marker of human origin by WB, IP, IF and IHC(P)
  • See Melanoma Marker (HMB45): sc-59305 for Melanoma Marker antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Melanoma Marker Antibody (NKI/C3) for WB and IHC(P) applications. These reagents are now offered in bundles with Melanoma Marker Antibody (NKI/C3) (see ordering information below).
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    Melanoma Marker Antibody (NKI/C3) is a mouse monoclonal IgG1 antibody that detects Melanoma Marker in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Melanoma Marker (NKI/C3) monoclonal antibody plays a crucial role in the study of malignant melanoma, a serious form of skin cancer that arises from melanocytes, the pigment-producing cells responsible for melanin synthesis. Understanding Melanoma Marker′s structure is vital, as this protein is involved in critical cellular processes such as cell adhesion and migration, which are essential for the metastasis of melanoma cells. Melanoma Marker′s structure allows for interaction with specific receptors and signaling pathways that regulate cell growth and survival, making this protein a key player in tumor progression. Anti-Melanoma Marker antibody (NKI/C3) helps researchers gain insights into the mechanisms of melanoma development and progression, ultimately aiding in the identification of potential therapeutic targets and improving patient outcomes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Melanoma Marker Antibody (NKI/C3) References:

    1. Evaluation of the serum L-dopa/L-tyrosine ratio as a melanoma marker.  |  Stoitchkov, K., et al. 2003. Melanoma Res. 13: 587-93. PMID: 14646622
    2. Ultra-structural cell distribution of the melanoma marker iodobenzamide: improved potentiality of SIMS imaging in life sciences.  |  Guerquin-Kern, JL., et al. 2004. Biomed Eng Online. 3: 10. PMID: 15068483
    3. Identification of a melanoma marker derived from melanoma-associated endogenous retroviruses.  |  Humer, J., et al. 2006. Cancer Res. 66: 1658-63. PMID: 16452225
    4. The new face of nucleolin in human melanoma.  |  Hoja-Łukowicz, D., et al. 2009. Cancer Immunol Immunother. 58: 1471-80. PMID: 19363676
    5. B16 melanoma secretomes and in vitro invasiveness: syntenin as an invasion modulator.  |  Rondepierre, F., et al. 2010. Melanoma Res. 20: 77-84. PMID: 20016392
    6. Significance of 5-S-Cysteinyldopa as a Marker for Melanoma.  |  Wakamatsu, K., et al. 2020. Int J Mol Sci. 21: PMID: 31936623
    7. Distinguishing melanophages from tumor in melanoma patients treated with talimogene laherparepvec.  |  Audrey-Bayan, C., et al. 2020. Melanoma Res. 30: 410-415. PMID: 32379409
    8. Investigating Serum and Tissue Expression Identified a Cytokine/Chemokine Signature as a Highly Effective Melanoma Marker.  |  Cesati, M., et al. 2020. Cancers (Basel). 12: PMID: 33302400
    9. PRAME Expression in Endometrioid and Serous Endometrial Carcinoma: A Potential Immunotherapeutic Target and Possible Diagnostic Pitfall.  |  Coppock, JD., et al. 2023. Int J Gynecol Pathol. 42: 35-42. PMID: 35512215
    10. MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance.  |  Arasi, MB., et al. 2024. Mol Ther. 32: 152-167. PMID: 37990493

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Melanoma Marker Antibody (NKI/C3)

    sc-52351
    200 µg/ml
    $322.00

    Melanoma Marker Antibody (NKI/C3): m-IgG Fc BP-HRP Bundle

    sc-536853
    200 µg Ab; 10 µg BP
    $361.00

    Melanoma Marker Antibody (NKI/C3): m-IgGκ BP-HRP Bundle

    sc-534020
    200 µg Ab; 40 µg BP
    $361.00

    Melanoma Marker Antibody (NKI/C3): m-IgG1 BP-HRP Bundle

    sc-544859
    200 µg Ab; 20 µg BP
    $361.00

    What is the recommended secondary for Melanoma Marker (NKI/C3): sc-52351 monoclonal antibody?

    Asked by: Trav11
    Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-03-07
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    Rated 5 out of 5 by FL from Positive signal detected in C32 and SKPositive signal detected in C32 and SK-MEL-24 whole cell lysates in WB. -SCBT QC
    Date published: 2015-03-05
    Rated 5 out of 5 by LR from Robust band detected in SKRobust band detected in SK-MEL-24, SK-MEL-28 and A-375 whole cell lysates in WB. -SCBT QC
    Date published: 2014-02-19
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    Melanoma Marker Antibody (NKI/C3) is rated 5.0 out of 5 by 2.
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